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TranscriptomicsGene expression profiles of MBP-specific T cells during experimental autoimmune encephalomyelitis
2nd generation sequencing was used to compare expression profiles of MBP-specific T cells retrieved from blood, CSF, spinal cord meninges and parenchyma. The overall expression profiles were found to be very similar.However, genes regulated during T cell activation were found to be upregulated in T ...
ORGANISM(S): Rattus norvegicus 
2016-02-12 | E-GEOD-75488 | biostudies-arrayexpress
UnknownRisk of Thrombus Fragmentation during Endovascular Stroke Treatment.
Not available
S-EPMC7960366 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis inflorescence stalks of intact plants after infection with A. tumefaciens
The intention of these gene expression analysis was to study host responses to an infection with Agrobacterium tumefaciens at different stages of crown gall development. Therefore the transcriptome of infected inflorescence stalk tissue and mature crown galls of Arabidopsis thaliana (WS-2) was deter...
ORGANISM(S): Arabidopsis thaliana 
2009-12-02 | E-GEOD-14106 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Arabidopsis after infection with different strains of Agrobacterium tumefaciens
This study focuses on responses of the host plant to infection with Agrobacterium tumefaciens. Genome wide changes in gene expression were integrated with the alterations in metabolite levels three hours after inoculation of agrobacteria. Plants were infected with the virulent strain C58, harboring ...
ORGANISM(S): Arabidopsis thaliana 
2009-12-02 | E-GEOD-13929 | biostudies-arrayexpress
ProteomicsSgt1 interactome analysis under proteostatic stress and steady state conditions
Buildup of misfolded proteins are prevented by chaperone-assisted refolding and/or proteasome dependent degradation. The coordination of these two protein quality control (PQC) systems is not fully understood. We identified the essential Hsp90 co-chaperone Sgt1 as a new member of a general PQC linki...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-07-02 | PXD016174 | Pride
Heat shock Sgt1 Hapi Saccharomyces cerevisiae Protein quality control 
UnknownPROTAC-mediated activation, rather than degradation, of a nuclear receptor reveals complex ligand-receptor interaction network.
Not available
S-EPMC11647748 | biostudies-literature
UnknownSubtle changes in ligand-receptor interactions dramatically alter transcriptional outcomes of pregnane X receptor modulators.
Not available
S-EPMC12690452 | biostudies-literature
TranscriptomicsTranscription profiling of Methanosarcina mazei Goe1 in response to bismuth nitrate.
Pattern of gene expression of M. mazei in response to 10 uM bismuth nitrate was analyzed relative to gene expression pattern of M. mazei grown in the presence of 30 uM potassium nitrate (control cultures). Therefore, five pre-cultures of M. mazei was grown to mid-exponential growth-phase. Then, the ...
ORGANISM(S): Methanosarcina mazei 
2011-10-01 | E-MTAB-787 | biostudies-arrayexpress
UnknownChemical manipulation of an activation/inhibition switch in the nuclear receptor PXR.
Not available
S-EPMC11094003 | biostudies-literature
TranscriptomicsDivergent genome expression profiles during hepatic ischemia in young and adult mice
Experimental Design: 1. The goal of the experiment: Age-Related Genome Expression Profiles During Hepatic Ischemia 2. Brief description of the experiment: Hepatic ischemia/reperfusion (I/R) injury is a complication of liver surgery, transplantation and shock and differs with age. In the present stu...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-10652 | biostudies-arrayexpress
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