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TranscriptomicsMicroarray-based CGH in human cancer cell lines
This series represents the data set from the paper Assembly of microarrays for genome-wide measurement of DNA copy number appearing in Nat Genet 2001 Nov;29(3):263-4 and it's web supplement. Specimen procurement, labeling, hybridization and imaging protocols from Nat Genet 2001 Nov;29(3):263-...
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-16 | biostudies-arrayexpress
TranscriptomicsOverexpression of GLI2 induces genomic instability
We used genome-wide microarray comparative genomic hybridization to investigate the response of control HT1080 cells and HT1080 cells infected with a lentivirus expressing eGFP, GLI2-eGFP or CCND1-RFP to challenge with methotrexate to address the question if GLI2 overexpression induces genomic insta...
ORGANISM(S): Homo sapiens 
2009-01-05 | E-GEOD-10132 | biostudies-arrayexpress
TranscriptomicsAssessment of basal cell carcinoma and rhabdomyosarcoma tumorigenesis in Blm-deficient Ptch1+/- mice
Basal cell carcinomas (BCCs) have relative genomic stability and relatively benign clinical behavior but whether these two are related causally is unknown. To investigate the effects of introducing genomic instability into murine BCCs, we have compared ionizing radiation-induced tumorigenesis in Pt...
ORGANISM(S): Mus musculus 
2010-05-15 | E-GEOD-19880 | biostudies-arrayexpress
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