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ProteomicsHexameric VCP/p97 reprograms transcription by organizing enhancers with the ASPSCR1-TFE3 fusion oncoprotein
Aberrant transcription in alveolar soft part sarcoma (ASPS) is orchestrated by the fusion oncoprotein, ASPSCR1-TFE3, resulting from a gene fusion created by a t(X;17) chromosomal translocation. Proteomic analysis of co-immunoprecipitated ASPSCR1-TFE3 complexes revealed strong enrichment of VCP/p97, ...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2023-11-23 | PXD022515 | Pride
Asps Ip-ms Tmt 
UnknownAlien plant invasions of protected areas in Java, Indonesia.
Not available
S-EPMC5570924 | biostudies-literature
UnknownNoncanonical Wnt signaling orchestrates early developmental events toward hematopoietic cell fate from human embryonic stem cells.
Not available
S-EPMC2742366 | biostudies-literature
UnknownCharacterization of the two conformations adopted by the T3SS inner-membrane protein PrgK.
Not available
S-EPMC6194235 | biostudies-literature
UnknownDose-adjusted EPOCH-rituximab combined with fludarabine provides an effective bridge to reduced-intensity allogeneic hematopoietic stem-cell transplantation in patients with lymphoid malignancies.
Not available
S-EPMC3295571 | biostudies-literature
MetabolomicsNMR based metabolomics study of Y2 receptor activation by neuropeptide Y in the SK-N-BE2 human neuroblastoma cell line
Neuropeptide Y (NPY) and its Y2 receptors (Y2R) play an important role in regulating growth of various tumors and are highly expressed in human neuroblastoma brain tumors. Cell lines derived from neuroblastoma brain tumors provide a good model to study the consequences of NPY activation of Y2R in tu...
2014-10-01 | MTBLS104 | MetaboLights
ProteomicsProteomic analysis of archival breast cancer clinical specimens identifies biological subtypes with distinct survival outcomes
Despite the advancement of genomic classification of breast cancer, current clinical tests and treatment decisions are commonly based on protein level information. Formalin-fixed paraffin-embedded (FFPE) tissue specimens are widely available and can be directly linked to extended clinical outcomes. ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD024322 | Pride
Proteomics Tmt Ffpe Breast cancer 
Proteomics4-ONE as a Chemoselective Biological Glue for Site-Resolved Protein Crosslinking and Proteomic Profiling
Protein crosslinking governs structure, stability, and interaction networks in biology, yet current chemical crosslinkers lack selectivity, produce heterogeneous products, and require pre-installed cleavable handles for analysis. Here, we report a conceptually distinct strategy that harnesses the in...
ORGANISM(S): Homo sapiens (Human) 
2026-05-26 | PXD070252 | Pride
UnknownCritical Role of ADAMTS-4 in the Development of Sporadic Aortic Aneurysm and Dissection in Mice.
Not available
S-EPMC5617887 | biostudies-literature
ProteomicsWhole proteome analysis of mesonephric-derived cancers describes new potential biomarkers
Mesonephric carcinomas (ME) and Female Adnexal Tumors of probable Wolffian Origin (FATWO) are thought to derive from remnants of the Wolffian/mesonephric ducts – anlages of the male reproductive tract. Mesonephric-like carcinomas (MLC) show identical morphology to ME of the cervix, but occur in the ...
ORGANISM(S): Homo sapiens (Human) 
2020-11-02 | PXD020879 | Pride
Tmt Mesonephric 
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