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UnknownIncisional hernia following colorectal cancer surgery according to suture technique: Hughes Abdominal Repair Randomized Trial (HART).
Not available
S-EPMC10364691 | biostudies-literature
GenomicsA role for Snf2 related nucleosome spacing enzymes in genome-wide nucleosome organization
The positioning of nucleosomes within the coding regions of eukaryotic genes is aligned with respect to transcriptional start sites. This organization is likely to influence many genetic processes, requiring access to the underlying DNA. Here we show that the combined action of Isw1 and Chd1 nucleos...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-16 | E-GEOD-31015 | biostudies-arrayexpress
UnknownThe histone chaperones Vps75 and Nap1 form ring-like, tetrameric structures in solution.
Not available
S-EPMC4027167 | biostudies-literature
UnknownThe PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4.
Not available
S-EPMC3437443 | biostudies-literature
TranscriptomicsA role for Snf2 related nucleosome spacing enzymes in genome-wide nucleosome organization
The positioning of nucleosomes within the coding regions of eukaryotic genes is aligned with respect to transcriptional start sites. This organization is likely to influence many genetic processes, requiring access to the underlying DNA. Here we show that the combined action of Isw1 and Chd1 nucleos...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-01 | E-GEOD-31833 | biostudies-arrayexpress
TranscriptomicsInfluence of SUMOylation on transcriptional signature of hIPSCs (ChiPS4) assessed by time-resolved RNA-seq in response to ML792 treatment
SUMOylation is thought to regulate chromatin structure and accessibility thus affecting gene expression. In order to assess these potential roles of SUMOylation in human pluripotent stem cells, ChiPS4 cells were treated with ML792 (selective SUMO E1 inhibitor) or DMSO (vehicle control) for the follo...
ORGANISM(S): Homo sapiens 
2022-12-01 | E-MTAB-9962 | biostudies-arrayexpress
TranscriptomicsInfluence of SUMOylation on chromatin structure in hIPSCs (ChiPS4) assessed by time-resolved ATAC-seq in response to ML792 treatment
SUMOylation is thought to regulate chromatin structure and accessibility thus affecting gene expression. In order to assess these potential roles of SUMOylation in human pluripotent stem cells, ChiPS4 cells were treated with ML792 (selective SUMO E1 inhibitor) or DMSO (vehicle control) for the follo...
ORGANISM(S): Homo sapiens 
2022-12-01 | E-MTAB-9961 | biostudies-arrayexpress
UnknownStructural plasticity of histones H3-H4 facilitates their allosteric exchange between RbAp48 and ASF1.
Not available
S-EPMC3538076 | biostudies-literature
UnknownMinocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration.
Not available
S-EPMC5837493 | biostudies-literature
ProteomicsMetabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | MassIVE
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