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MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
TranscriptomicsTranscription profiling of Baseline gene expression in circulating peripheral blood mononuclear cells isolated from 18 apparently healthy volunteers (10 females and 8 males)
Baseline gene expression in circulating peripheral blood mononuclear cells isolated from 18 apparently healthy volunteers (10 females and 8 males). The volunteers fasted overnight for 10 hours prior to collection of blood samples (but they were allowed water). 5 blood samples were collected from eac...
ORGANISM(S): Homo sapiens 
2013-01-30 | E-TABM-7 | biostudies-arrayexpress
UnknownThe odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR.
Not available
S-EPMC7668088 | biostudies-literature
GenomicsLimitations and possibilities of low cell number ChIP-seq
ChIP-seq experiments using low numbers of input cells, scaled down to the point where data quality is unnacceptably compromised, reveals limits of the technique. Two-part ChIPseq study using native chromatin (non-crosslinked) generated with MNase from human CD4+ cells. Part 1: Previously published p...
ORGANISM(S): Homo sapiens 
2012-12-03 | E-GEOD-42147 | biostudies-arrayexpress
TranscriptomicsThe Sen1 Helicase Prevents Spurious Transcription by Controlling Genome-Wide Transcription Termination by RNAPII
RNA Polymerase II (RNAPII) termination for transcripts containing a polyadenylation signal (PAS) is thought to differ mechanistically from termination for PAS-independent RNAPII transcripts such as sn(o)RNAs. In a screen for factors required for PAS-dependent termination, we identified Sen1, a putat...
ORGANISM(S): Saccharomyces cerevisiae 
2011-06-01 | E-GEOD-19015 | biostudies-arrayexpress
GenomicsPCGP Ph-like ALL
Background: BCR-ABL1-like, or Ph-like acute lymphoblastic leukemia is characterized by a gene expression profile similar to BCR-ABL1 positive ALL, genetic alterations of lymphoid transcription factor genes, and poor outcome. Sequencing of small numbers of Ph-like ALL cases has identified genetic alt...
EGAS00001000654 | EGA
UnknownDeveloping standardized corticosteroid treatment for Duchenne muscular dystrophy.
Not available
S-EPMC6279424 | biostudies-literature
GenomicsPCGP Ph-likeALL RNASeq - samples
DATA FILES FOR SJPhLike-RNASeq
EGAD00001001016 | EGA
GenomicsPCGP Ph-likeALL SNP6 - samples
PCGP Ph-likeALL SNP6
EGAD00010000598 | EGA
GenomicsPCGP Ph-likeALL WES - samples
DATA FILES FOR Ph-likeALL WES
EGAD00001001054 | EGA
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