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MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (V. parahaemolyticus-infected spleen metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7996 | MetaboLights
MetabolomicsCyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine and human plasma quantitative L-arginine and methylarginines UPLC-MS/MS assay)

BACKGROUND: Large-scale, placebo-controlled trials established that nonsteroidal anti-inflammatory drugs confer a cardiovascular hazard: this has been attributed to depression of cardioprotective products of cyclooxygenase (COX)-2, especially prostacyclin. An alternative mechanis...

2019-08-22 | MTBLS685 | MetaboLights
UnknownPrevalence of hyperuricaemia among adults from Ningxia Hui Autonomous Region, China: a cross-sectional study.
Not available
S-EPMC10603489 | biostudies-literature
MetabolomicsEffects of Leuconostoc lactis on the antioxidant ability and indole-3-acetaldehyde metabolism via regulating the gut microbiota-liver axis in aged laying hens

Lactobacillus has antioxidant properties that may benefit poultry production. However, there is no systematic research on antioxidant of Lactobacillus strain and its effects on regulating nutrient metabolism in aged laying hens. This study investigated the influence of Leuconostoc lactis on produ...

2025-09-09 | MTBLS12964 | MetaboLights
ProteomicsIntegrative genomic and proteomic analysis of response of Lactobacillus casei str. Zhang to glucose limitation
Nutrient starvation is an important survival challenge for bacteria during industrial production of functional foods. Lactobacilli are increasingly being used as probiotics in functional foods. As next-generation sequencing technology has greatly advanced, we performed integrative proteomic and geno...
ORGANISM(S): Lactobacillus casei str. Zhang 
2018-02-08 | PXD006643 | Pride
Lactobacillus casei str. zhang  lace of glucose 
TranscriptomicsMediator Complex Regulates Alternative mRNA Processing via the Med23 Subunit
Mediator complex is an integrative hub for transcriptional regulation. Here we show that Mediator regulates alternative mRNA processing via its Med23 subunit. Combining tandem affinity purification and mass spectrometry, we identified a number of mRNA processing factors that bind to a soluble recomb...
ORGANISM(S): Homo sapiens 
2012-02-24 | E-GEOD-33771 | biostudies-arrayexpress
GenomicsMediator Complex Regulates Alternative mRNA Processing via the Med23 Subunit
Mediator complex is an integrative hub for transcriptional regulation. Here we show that Mediator regulates alternative mRNA processing via its Med23 subunit. Combining tandem affinity purification and mass spectrometry, we identified a number of mRNA processing factors that bind to a soluble recomb...
ORGANISM(S): Homo sapiens 
2012-02-24 | E-GEOD-33887 | biostudies-arrayexpress
TranscriptomicsHigh-throughput sequencing analysis identify miRNAs in 7dpf F1-zebrafish under β-diketone antibiotics exposure to F0-zebrafish
Small RNA high-throughput sequencing technology was used to characterize the miRNAs in F1-zebrafish after 90-day β-diketone antibiotic (DKA) exposure to F0-zebrafish at 6.25 and 12.5 mg/L. The small RNA libraries from 7-dpf F1-zebrafish were constructed. In total, 10,117,347, 9,818,830 and 12,049,...
ORGANISM(S): Danio rerio 
2016-07-30 | E-GEOD-85004 | biostudies-arrayexpress
UnknownInverted U-shaped associations between serum uric acid and fasting - plasma glucose level in non-diabetic, pre-diabetic, and diabetic adults: A population-based study in China.
Not available
S-EPMC10981146 | biostudies-literature
TranscriptomicsGrowth and Secondary Metabolite Responses to Different UV Wavelength in Canola (Brassica napus L.) in a Plant Factory with Artificial Light
This study aimed to evaluate the effects of UV-B wavelength regions (< 300 nm) in canola plants (Brassica napus L.). Agilent One-Color Gene Expression Microarray analysis was conducted using an Agilent-022520 Brassica napus 4x44K Array.
ORGANISM(S): Brassica napus 
2022-03-18 | E-MTAB-11596 | biostudies-arrayexpress
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