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MetabolomicsMetabolomics revealed the influence of breast cancer on lymphatic endothelial cell metabolism, metabolic crosstalk, and lymphangiogenic signaling in co-culture

Breast cancer metastasis occurs via blood and lymphatic vessels. Breast cancer cells 'educate' lymphatic endothelial cells (LECs) to support tumor vascularization and growth. However, despite known metabolic alterations in breast cancer, it remains unclear how lymphatic endothelial cell metabolis...

2024-06-25 | MTBLS859 | MetaboLights
GenomicsOncogenic ETS proteins replace activated Ras/MAPK signaling in prostate cells.
Approximately 50% of prostate cancers have chromosomal translocations resulting in the over-expression one of four ETS family transcription factors. However, it is not known why these four four family members are selected for oncogenic roles, while other ETS proteins are not. We found that the four...
ORGANISM(S): Homo sapiens 
2011-10-19 | E-GEOD-29808 | biostudies-arrayexpress
UnknownGAD-alum immunotherapy in type 1 diabetes expands bifunctional Th1/Th2 autoreactive CD4 T cells.
Not available
S-EPMC7228993 | biostudies-literature
TranscriptomicsOncogenic ETS proteins regulate a Ras/MAPK gene expression program in the absence of MAPK signaling
Approximately 50% of prostate cancers have chromosomal translocations resulting in the over-expression one of four ETS family transcription factors. However, it is not known why these four four family members are selected for oncogenic roles, while other ETS proteins are not. We found that the four...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-29438 | biostudies-arrayexpress
UnknownRituximab plus chlorambucil as first-line treatment for chronic lymphocytic leukemia: Final analysis of an open-label phase II study.
Not available
S-EPMC4876343 | biostudies-literature
UnknownAspirin versus placebo for the treatment of venous leg ulcers-a phase II, pilot, randomised trial (AVURT).
Not available
S-EPMC6660698 | biostudies-literature
UnknownMaturation of iPSC-derived cardiomyocytes in a heart-on-a-chip device enables modeling of dilated cardiomyopathy caused by R222Q-SCN5A mutation.
Not available
S-EPMC10942743 | biostudies-literature
GenomicsMapping and dynamics of regulatory DNA in A. thaliana tissues and cell types across developmental transitions
We performed DNase-seq on root tissue, root epidermal cell types, seed coat epidermal cells at two developmental stages, and open and closed flowers. Root: We performed chromatin profiling (DNase-seq) on whole root (all cell types), or root epidermal cell types (hair cell, non-hair cell). Seed coat:...
ORGANISM(S): Arabidopsis thaliana 
2013-12-15 | E-GEOD-53324 | biostudies-arrayexpress
UnknownFinal Report of the Intergroup Randomized Study of Combined Androgen-Deprivation Therapy Plus Radiotherapy Versus Androgen-Deprivation Therapy Alone in Locally Advanced Prostate Cancer.
Not available
S-EPMC4477786 | biostudies-literature
UnknownIn silico prediction of optimal multifactorial intervention in chronic kidney disease.
Not available
S-EPMC12372250 | biostudies-literature
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