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We report on explant osteoblast cultures from human patients, demonstrating that there are at least three sub-types of non-syndromic craniosynostosis defined by similarity of gene expression profiles. Osteoblast growth in culture, 23 craniosynostosis skull samples (7 metopic; 8 coronal; 3 lambdoid; ...
ORGANISM(S): Homo sapiens 
Metabolomics is a modern tool that aids in our understanding of the molecular changes in organisms. Archaeological science is a branch of archaeology that explores different archaeological materials using modern analytical tools. Human osteoarchaeological material are a frequent finding in archaeolo...
2022-07-04 | MTBLS4437 | MetaboLights
Ancient pathogen DNA in human teeth and petrous bones
Genome-wide Methylation Profiles of femoral bones

BACKGROUND: Ischemia/reperfusion injury (IRI) is the leading cause of acute kidney injury (AKI). The current standard of care focuses on supporting kidney function, stating the need for more efficient and targeted therapies to enhance repair. Mesenchymal Stromal Cells (MSCs) and ...

2023-10-16 | MTBLS6279 | MetaboLights

This dataset was generated to elucidate the metabolic features of femoral neck osteoporosis, a major risk factor for fractures and bedbound states in the elderly. Using whole-blood metabolomics, we analyzed the metabolic profiles of elderly individuals with and without femoral neck osteoporo...

2026-01-08 | MTBLS11650 | MetaboLights
Genome-wide DNA methylation profiling of femoral bones obtained from young and old individuals. The Illumina Infinium HumanMethylation EPIC BeadChip was used to obtain DNA methylation profiles across approximately 850K CpGs from human femoral bones.
ORGANISM(S): Homo sapiens 
2020-02-26 | GSE138307 | GEO
Investigation of differentially-expressed microRNAs involved in infected nonunion of the human long bones through microRNA expression profiling
In search of markers for protein aging, we used an extraordinary test case of human bones from the excavations sites of Pompei and Herculaneum (79 AD), analyzed by a shotgun proteomic approach using LC-MS/MS. Human bones from Scalandrone Bay (II sec AD, another volcanic area, yet not related to Vesu...
ORGANISM(S): Homo sapiens (Human) 
2021-07-10 | PXD020462 | Pride
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