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GenomicsGenome-scale CRISPR knockout screen for Dengue, Japanese Encephalitis, and Human Coronavirus 229E viruses
Unbiased forward genetic screens to identify host factors for DENV1 and JEV in 293FT cells. Unbiased forward genetic screens to identify host factors for HCoV-229E in Huh7.5.1 cells.
ORGANISM(S): Homo sapiens 
2024-09-13 | E-MTAB-13751 | biostudies-arrayexpress
TranscriptomicsFunctional genomic screens in human cells to identify host factors for SARS-CoV-2 and common cold coronaviruses
We performed genome-wide CRISPR KO screens in human Huh7.5.1 cells to select for mutations that render host cells resistant to viral infection by SARS-CoV-2, human coronavirus 229E and OC43.
ORGANISM(S): Homo sapiens 
2020-10-16 | E-MTAB-9638 | biostudies-arrayexpress
ProteomicsHuman coronavirus-229E infection alters the structure of host RNA processing complexes
The purpose of this experiment was to evaluate the human host cellular response to wild-type human coronavirus strain 229E (HCoV-229E)(ncbitaxon:11137) infection. Sample data was obtained for mock and infected (MOI 3) immortalized human lung epithelial cells (A549), immortalized human lung fibroblas...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-11-05 | MSV000096303 | MassIVE
GenomicsTemperature and developmental stage govern intestinal susceptibility to human coronavirus 229E.
Temperature and developmental stage govern intestinal susceptibility to human coronavirus 229E.
PRJNA1427667 | ENA
ProteomicsHuman coronavirus-229E infection alters the structure of host RNA processing complexes
The purpose of this experiment was to evaluate the human host cellular response to wild-type human coronavirus strain 229E (HCoV-229E)(ncbitaxon:11137) infection. Sample data was obtained for mock and infected (MOI 3) immortalized human lung epithelial cells (A549), immortalized human lung fibroblas...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-31 | MSV000096268 | MassIVE
TranscriptomicsLongitudinal clonal IgG cross-reactivity profiles of coronavirus-specific B-cells in COVID-19 patients
We investigated the kinetics, breadth, magnitude, and level of cross-reactivity of IgG antibodies against SARS-CoV-2 and heterologous seasonal (HCoV-NL63, -229E, -OC43 and -HKU1) and epidemic coronaviruses (SARS-CoV, hCoV-MERS) at the clonal level in patients with mild or severe COVID-19 as well as ...
ORGANISM(S): Homo sapiens 
2022-09-30 | E-MTAB-12161 | biostudies-arrayexpress
TranscriptomicsTemperature and developmental stage govern intestinal susceptibility to human coronavirus 229E.
Transcriptional profiling of fetal, pediatric, and adult human intestinal enteroids following Human Coronavirus 229E infection at 32C and 37C.
ORGANISM(S): Homo sapiens 
2026-03-01 | GSE320363 | GEO
GenomicsZBTB7A promotes virus-host homeostasis during human coronavirus 229E infection I
ZBTB7A promotes virus-host homeostasis during human coronavirus 229E infection I
PRJNA811447 | ENA
ProteomicsEffect of a functional dairy powder and its major components on the growth of pathogenic and probiotic gut bacteria and the Human Coronavirus 229E
Milk, renowned for its nutritional value, harbours bioactive compounds, including lactoferrin (Lf) [1], immunoglobulins, and functional proteins suggesting broader functionalities beyond nutrition. Lf, an iron glycoprotein, exhibits antimicrobial properties against bacteria, fungi, and viruses."In"t...
ORGANISM(S): Homo sapiens (Human) 
2024-12-02 | PXD052339 | Pride
Probiotic Antibacterial In vitro digestion Human coronavirus 229e Antifungal Anti-inflammatory Functional milk product Proteomics Gut bacteria 
GenomicsHuman Primary Airway Epithelium Response to HCoV-229E Infection
Human Primary Airway Epithelium Response to HCoV-229E Infection
PRJNA1172745 | ENA
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