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TranscriptomicsRole of BACH1 in HEK 293T cells
This SuperSeries is composed of the following subset Series: GSE28050: Expression data from knockdown of BACH1 in HEK 293T cells GSE28051: Genome-wide map of BACH1 binding in HEK293T cells Refer to individual Series
ORGANISM(S): Homo sapiens 
2011-05-12 | E-GEOD-28053 | biostudies-arrayexpress
GenomicsGenome-wide map of BACH1 binding in HEK 293T cells
BTB and CNC homology 1 (BACH1) is a heme-binding transcription factor repressing the transcription from a subset of MAF recognition elements (MAREs) at low intracellular heme levels. Upon heme binding, BACH1 is released from the MAREs, resulting in increased expression of antioxidant response genes....
ORGANISM(S): Homo sapiens 
2011-05-13 | E-GEOD-28051 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human HEK-293T cells treated with a nutraceutical formula (solution-10), or vehicle-(saline solution)- control
HEK-293T cells were plated (1x106 cells) and treated with a nutraceutical formula (Solution-10) at 0.01x concentration or with vehicle (saline solution) as the negative control for the treatment. After 24 hours, the cells were lysed, and their RNA was extracted for RNAseq.
ORGANISM(S): Homo sapiens 
2026-08-14 | E-MTAB-17521 | biostudies-arrayexpress
TranscriptomicsExpression data from knockdown of BACH1 in HEK 293T cells
BTB and CNC homology 1 (BACH1) is a heme-binding transcription factor repressing the transcription from a subset of MAF recognition elements (MAREs) at low intracellular heme levels. Upon heme binding, BACH1 is released from the MAREs, resulting in increased expression of antioxidant response genes....
ORGANISM(S): Homo sapiens 
2011-05-13 | E-GEOD-28050 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human HEK-293T cells treated with a nutraceutical formula (solution-3), or vehicle-(saline solution)-treated controls
HEK-293T cells were plated (1x106 cells) and treated with a nutraceutical formula (solution-3) at 0.01x concentration or with vehicle (saline solution) as the negative control for the treatment. After 24 hours, the cells were lysed, and their RNA was extracted for RNAseq.
ORGANISM(S): Homo sapiens 
2024-06-19 | E-MTAB-13918 | biostudies-arrayexpress
TranscriptomicsGene expression data from HEK-293T cells transfected with miR-194 mimics
Nuclear factor κB (NF-κB) pathway plays an important role in hepatocellular carcinoma (HCC) progression. miR-194 was previously shown to reduce the induction of NF-κB activity upon addition of tumor necrosis factor α (TNFα). To clarify the molecular mechanism responsible for the effect of miR-194 on...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-70434 | biostudies-arrayexpress
TranscriptomicsQuantitative real-time RT-PCR analysis of HEK293 cells stably transfected with PRL-1 (PTP4A1) or empty pcDNA4 vector control.
The protein tyrosine phosphatase PRL-1 (Gene Symbol: PTP4A1) has been identified as an important oncogene with roles in promoting cell proliferation, survival, migration, invasion, and metastasis. However, little is currently known about the signaling pathways through which it mediates its effects...
ORGANISM(S): Homo sapiens 
2013-07-30 | E-GEOD-42587 | biostudies-arrayexpress
MetabolomicsPhenotypes and Multi—omics Reveal Changes and Molecular Mechanism of Suspension Adaptation of HEK293 Cells Structural Remodelling, Metabolic Reconstruction and Stress Resistance

Human embryonic kidney 293 (HEK293) cells have been successfully adapted from adherent to suspension culture and have been widely applied in both scientific research and the pharmaceutical industry. However, the alterations in cells during the adaptation have not been well described, which raise ...

2025-12-16 | MTBLS13517 | MetaboLights
TranscriptomicsHEK 293T cells RNA-seq data treated with 5-aza-2-deoxycytidine
DNA methylation can be abnormally regulated in human disease and associated with effects on gene transcription that appear to be causally related to pathogenesis. The potential to use pharmacological agents that reverse this dysregulation is therefore an attractive possibility. To test how 5-aza-2...
ORGANISM(S): Homo sapiens 
2015-02-13 | E-GEOD-62591 | biostudies-arrayexpress
TranscriptomicsAlteration of gene expression in HEK 293T cells upon inhibition of PCAF by embelin
KAT2B (PCAF) belongs to GNAT family of lysine acetyltransferases (KAT), which specifically acetylates histone H3K9 residue and several nonhistone proteins. PCAF is also a transcription coactivator. Due to the lack of PCAF, KAT specific small molecule inhibitor, the exclusive role of the acetyltransf...
ORGANISM(S): Homo sapiens 
2013-03-31 | E-GEOD-39828 | biostudies-arrayexpress
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