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ProteomicsZIKV-infected human NPCs LC-MS
In this study, proteomic analysis on ZIKV-infected primary human fetal neural progenitor cells (NPCs) revealed that virus infection altered levels of cellular proteins involved in NPC proliferation, differentiation and migration.
ORGANISM(S): Homo sapiens (Human) 
2018-06-25 | PXD009343 | Pride
Human npcs Zikv infection 
MetabolomicsNeurotoxicity of Propylene Glycol Butyl Ether: Multiomic Evidence from Human BrainSpheres

Exposure to solvents may contribute to the development of neurodevelopmental and neurodegenerative diseases. Glycol ethers consist in a widely used class of organic solvents leading to workers and consumers exposure via many different applications. Ethylene glycol ethers are gradually being repla...

2026-08-25 | MTBLS12921 | MetaboLights
MetabolomicsNeurotoxicity of Propylene Glycol Butyl Ether: Multiomic Evidence from Human BrainSpheres

Exposure to solvents may contribute to the development of neurodevelopmental and neurodegenerative diseases. Glycol ethers consist in a widely used class of organic solvents leading to workers and consumers exposure via many different applications. Ethylene glycol ethers are gradually being repla...

2026-08-25 | MTBLS12771 | MetaboLights
TranscriptomicsHuman induced pluripotent stem cell-technology to study the effects of human cytomegalovirus infection on neural differentiation
Congenital human cytomegalovirus (HCMV) infection is one of the leading prenatal causes of mental retardation and congenital deformities world-wide. Access to cultured human neuronal lineages, necessary to understand the species specific pathogenic effects of HCMV has been limited by difficulties i...
ORGANISM(S): Homo sapiens 
2013-01-04 | E-GEOD-35295 | biostudies-arrayexpress
GenomicsZIKV infection strongly induces antiviral immune responses in human NPCs
ZIKV infection strongly induces antiviral immune responses in human NPCs
PRJNA530400 | ENA
TranscriptomicsComparing Control and Schizophrenic hiPSC-derived NPCs
Cell-based models of many neurological and psychiatric diseases, established by reprogramming patient somatic cells into human induced pluripotent stem cells (hiPSCs), have now been reported. While numerous reports have demonstrated that neuronal cells differentiated from hiPSCs are electrophysiolo...
ORGANISM(S): Homo sapiens 
2014-04-01 | E-GEOD-40102 | biostudies-arrayexpress
TranscriptomicsDifferentiation of human fetal multipotential neural progenitor cells to astrocytes reveals susceptibility factors for JC Virus
Viral infections of the CNS are of increasing concern, especially among immunocompromised populations. Rodent models are often inappropriate for studies of CNS infection, as many viruses, including JC Virus (JCV) and HIV, cannot replicate in rodent cells. Consequently, human fetal brain-derived mult...
ORGANISM(S): Homo sapiens 
2013-04-09 | E-GEOD-43794 | biostudies-arrayexpress
TranscriptomicsNext Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs
Cell-based models of many neurological and psychiatric diseases, established by reprogramming patient somatic cells into human induced pluripotent stem cells (hiPSCs), have now been reported. While numerous reports have demonstrated that neuronal cells differentiated from hiPSCs are electrophysiolo...
ORGANISM(S): Homo sapiens 
2016-03-14 | E-GEOD-63738 | biostudies-arrayexpress
GenomicsENTA-011 and BDNF transcriptomic effects on human NPCs
Transcriptomic comparison of the effects of ENTA-011 and BDNF treatment in human iPSC derived NPCs
PRJEB62550 | ENA
TranscriptomicsATAC-seq of iPSC-derived NPCs and neurons
To connect the neuronal developmental disorders associated GWAS signal to their target effector genes, we performed an integrated analysis of transcriptomics, epigenomics and chromatin conformation changes in an in vitro cellular model. Induced human pluripotent stem cell–derived neural progenitor c...
ORGANISM(S): Homo sapiens 
2021-05-27 | E-MTAB-9087 | biostudies-arrayexpress
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