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ProteomicsNew insights into the architecture of the human SMC5/6 complex
A family of Structural Maintenance of Chromosome (SMC) complexes is essential for key cellular processes ensuring proper cohesion, condensation and replication. They share common SMC-kleisin architecture allowing them to embrace DNA. The prokaryotic and eukaryotic SMC5/6 complexes contain additional...
ORGANISM(S): Homo sapiens (Human) 
2023-08-18 | PXD017379 | Pride
Cross-linking mass spectrometry Human smc5/6 complex architecture  nse1-nse3-nse4 trimer  nse5-nse6 dimer  protein-protein interactions 
UnknownThe SMC5/6 complex: folding chromosomes back into shape when genomes take a break.
Not available
S-EPMC10954462 | biostudies-literature
UnknownLarge-scale phenogenomic analysis of human cancers uncovers frequent alterations affecting SMC5/6 complex components in breast cancer.
Not available
S-EPMC10495288 | biostudies-literature
UnknownThe SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis.
Not available
S-EPMC4807058 | biostudies-literature
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