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UnknownEmpagliflozin Improves Insulin Sensitivity of the Hypothalamus in Humans With Prediabetes: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial.
Not available
S-EPMC8914418 | biostudies-literature
ProteomicsCSF proteomics of aducanumab treated APP-SAA triple knock-in mice
Anti-amyloid β-peptide (Aβ) immunotherapy was developed as treatment for Alzheimer’s disease to reduce and prevent amyloid plaque pathology and its downstream consequences. Efficient amyloid plaque clearance has been proven in clinical trials with Aducanumab, Lecanemab and Donanemab. At least two of...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-25 | PXD061932 | Pride
Cerebrospinal fluid Mouse Diapasef Aducanumab 
TranscriptomicsGenetic targets of hydrogen sulfide in ventilator-induced lung injury
In this study we provide evidence on potential mechanisms involved in H2S mediated protection against VILI. H2S down-regulates genes that are involved in oxidative stress and pro-inflammatory cell responses. H2S regulates ECM remodelling, a mechanism which may contribute to H2S-mediated lung protect...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-58169 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in isogenic p53wt/p53ko Burkitt lymphoma cell line Seraphine after shRNA-mediated knock-down of p53 pathway members
We performed an shRNA-based RNAi interference screen targeting around 5,000 genes in eight Burkitt lymphoma cell lines. MDM4 and CDKN3 were essential genes in four p53 wild-type Burkitt lymphoma cell lines, but not in four p53 mutant cell lines. To investigate the effect of the gene knock-down on ce...
ORGANISM(S): Homo sapiens 
2019-08-01 | E-MTAB-7134 | biostudies-arrayexpress
TranscriptomicsTranslocations Activating IRF4 Identify a Subtype of Germinal-Center-Derived B-cell Lymphoma Affecting Predominantly Children and Young Adults
Background: Germinal center B-cell (GCB) lymphomas are common in children and adults. The prognosis strongly depends on age. Subgroups of GCB-lymphomas are characterized by chromosomal translocations affecting immunoglobulin (IG) loci leading to oncogene deregulation. Methods: Novel IG translocation...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-22470 | biostudies-arrayexpress
GenomicsWGSeq_HealthyHuman_DATA_SET_xmas_MB_2013_07_10 - samples
HSC73_clone: Bone marrow mononuclear cells from the healthy 73 years old female were thawed and labeled with Alexa-Fluor 488-conjugated anti-CD34 (581, Biolegend), Alexa-Fluor 700-conjugated anti-CD38 (HIT2, eBioscience), a cocktail of APC-conjugated lineage antibodies consisting of anti-CD4 (RPA-T4...
EGAD00001000666 | EGA
Genomicsrna_seq_data_freeze_march_2013_DATA_SET_MMML_2012_11_06 - samples
ICGC MMML-seq Data Freeze March 2013 transcriptome sequencing
EGAD00001000356 | EGA
GenomicsMMML_2012_11_06_Methylation450k_case - samples
DNA methylation analysis of 6 primary lymphoma samples
EGAD00010000377 | EGA
GenomicsWGSeq_RNAseq_ChIPseq_Cancer_ICGC_DATA_SET_xmas_MB_2013_07_10 - samples
Whole Genome Seq: Illumina HiSeq sequence data (with >30x coverage) were aligned to the hg19 human reference genome assembly using BWA (Li and Durbin, 2009); duplicate reads were removed from the final BAM file. No realignment or recalibration was performed. Paired-end RNA sequencing reads were mapp...
EGAD00001000664 | EGA
GenomicsRNA-Seq_DATA_SET_storm_MMML_2013_07_10 - samples
ICGC MMML-seq Data Freeze July 2013 transcriptome sequencing
EGAD00001000648 | EGA
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