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TranscriptomicsPolycistronic clustering characteristics of deregulated microRNA genes in triple-negative breast cancer revealed by deep sequencing
Twenty-four triple-negative breast cancer and 14 adjacent normal tissues were collected from breast cancer patients during surgeries at National Taiwan University Hospital (NTUH, Taipei, Taiwan). All triple-negative breast cancer samples were invasive ductal carcinomas (IDC) and were negative in imm...
ORGANISM(S): Homo sapiens 
2015-03-01 | E-GEOD-40049 | biostudies-arrayexpress
TranscriptomicsMolecular characteristics and metastasis predictor genes of triple-negative breast cancer (II)
This microarray dataset contains 51 triple-negative breast cancers, 25 normal breast tissues, and 106 luminal breast cancers (reanalyzed data from Series GSE24124, GSE9309, and GSE17040). Keywords: Expression profiling by array Specimens of breast cancer tissue were collected and snap-frozen from b...
ORGANISM(S): Homo sapiens 
2014-01-02 | E-GEOD-53752 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human 48 clinical breast cancer arrays to perform statistical identification of gene association by CID in application of constructing ER regulatory network
A variety of high-throughput techniques are now available for constructing comprehensive gene regulatory networks in systems biology. In this study, we report a new statistical approach for facilitating in silico inference of regulatory network structure. The new measure of association, coefficient ...
ORGANISM(S): Homo sapiens 
2009-07-19 | E-GEOD-17041 | biostudies-arrayexpress
TranscriptomicsMajor gene partners of a favorable biomarker in ER(+) breast cancer
Background: We have established a statistical approach on building a transcriptional regulatory network in silico at a global transcriptome scale. Here, we characterize clinical relevant gene activities regulated by a transcription factor-estrogen-related receptor gamma (ESRRG) via such approach. ...
ORGANISM(S): Homo sapiens 
2010-11-04 | E-GEOD-24124 | biostudies-arrayexpress
UnknownThree-dimensional genome landscape of primary human cancers.
Not available
S-EPMC12081301 | biostudies-literature
TranscriptomicsMajor functional transcriptome of an inferred center regulator of an ER(-) breast cancer model system
We aimed to find clinically relevant gene activities ruled by the signal transducer and activator of transcription 3 (STAT3) proteins in an ER(-) breast cancer population via network approach. STAT3 is negatively associated with both lymph nodal category and stage. MYC is a component of STAT3 networ...
ORGANISM(S): Homo sapiens 
2012-09-25 | E-GEOD-32641 | biostudies-arrayexpress
UnknownHigh-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Not available
S-EPMC7002524 | biostudies-literature
TranscriptomicsIdentification of Prognostic Genes for Recurrent Risk Prediction in Triple Negative Breast Cancer Patients in Taiwan
Discrepancies in the prognosis of triple negative breast cancer exist between Caucasian and Asian populations. Yet, the gene signature of triple negative breast cancer specifically for Asians has not become available. Therefore, the purpose of this study is to construct a prediction model for recu...
ORGANISM(S): Homo sapiens 
2012-02-02 | E-GEOD-33095 | biostudies-arrayexpress
UnknownComprehensive molecular characterization of mitochondrial genomes in human cancers.
Not available
S-EPMC7058535 | biostudies-literature
UnknownThe landscape of viral associations in human cancers.
Not available
S-EPMC8076016 | biostudies-literature
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