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TranscriptomicssiRNA of human MCF-7 cells
Overexpression of the AP-2γ transcription factor in breast tumours has been identified as an independent predictor of poor outcome and failure of hormone therapy, even in ER positive, ErbB2 negative tumours; markers of a more favourable prognosis. To understand further the role of AP-2γ in breast...
ORGANISM(S): Homo sapiens 
2009-12-19 | E-GEOD-15481 | biostudies-arrayexpress
TranscriptomicsGenotyping of human lung cancer cells on the 10K Affymetrix SNP array to validate whole genome amplification of genomic DNA from laser captured microdissectates and genotyping serial samples of developing lung cancers to identify early events
A series of experiments were performed to validate whole genome amplification of genomic DNA from laser captured microdissectates and the technique was then applied to serial samples of developing lung cancers to identify early events. 10K Affymetrix SNP arrays were used.
ORGANISM(S): Homo sapiens 
2006-10-01 | E-TABM-134 | biostudies-arrayexpress
UnknownHeterozygous loss-of-function variants in DOCK4 cause neurodevelopmental delay and microcephaly.
Not available
S-EPMC11043173 | biostudies-literature
UnknownGain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders.
Not available
S-EPMC10336078 | biostudies-literature
UnknownFrequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells.
Not available
S-EPMC4448678 | biostudies-literature
UnknownGenetic Testing to Inform Epilepsy Treatment Management From an International Study of Clinical Practice.
Not available
S-EPMC9623482 | biostudies-literature
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