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UnknownIntegrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.
Not available
S-EPMC5819607 | biostudies-literature
UnknownSpatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma.
Not available
S-EPMC7160105 | biostudies-literature
UnknownAnalysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.
Not available
S-EPMC5082984 | biostudies-literature
Genomicsena-DATASET-MDACC-31-10-2017-21:58:14:730-1118 - samples
This dataset contains WES data (.bam files) and associated phenotype information from 10 patients included in our microbiome study who went on to anti PD-1 immunotherapy for the treatment of metastatic melanoma at the University of Texas MD Anderson Cancer Center. Both tumor and matching germ line n...
EGAD00001003797 | EGA
Genomicsena-DATASET-MDACC-02-02-2018-10:54:47:473-560 - samples
The oral and gut microbiomes of melanoma patients were characterized before the initiation of ant-PD1 immunotherapy, and compared to treatment response. Validation studies were performed in germ-free mice using stool from patients who responded/did not respond to ant-PD1 immunotherapy. All baseline...
EGAD00001003943 | EGA
GenomicsGut microbiome modulates response to anti PD1 immunotherapy in metastatic melanoma patients
There is a growing appreciation of the role of the microbiome in cancer, and evidence in pre-clinical models that the gut microbiome may modulate responses to immune checkpoint blockade though this has not been well-characterized in patients. We analyzed the oral (n=86)and gut (n=43) 16S microbiome ...
EGAS00001002698 | EGA
GenomicsThis committee is composed on individuals who have access to the data corresponding to this project: Gut microbiome modulates response to anti PD-1 immunotherapy in melanoma patients
Data Access Committee EGAC00001000758
EGAC00001000758 | EGA
UnknownGut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade.
Not available
S-EPMC11107795 | biostudies-literature
UnknownEffect of Sickle Cell Trait and APOL1 Genotype on the Association of Soluble uPAR with Kidney Function Measures in Black Americans.
Not available
S-EPMC7863645 | biostudies-literature
UnknownImproving polygenic prediction in ancestrally diverse populations.
Not available
S-EPMC9117455 | biostudies-literature
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