Hybrid pks - OmicsDI

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CHEBI ID

CHEBI:167190 (1)
CHEBI:167189 (1)
CHEBI:167188 (1)
CHEBI:167187 (1)
CHEBI:167186 (1)
CHEBI:167185 (1)

Metabolite Name

2,2',2''-((2R,5R,8S,11R)-11-((2R,4S,5E,7E,9E)-2,4-dihydroxypentadeca-5,7,9-trien-1-yl)-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-2,5,8-triyl)triacetamide (1)
(3R,5R,7S,8E,10E,12E)-3-amino-5,7-dihydroxyoctadeca-8,10,12-trienoic acid (1)
(3-((3R,5R,7S,8E,10E,12E)-3-amino-5-hydroxy-7-methoxyoctadeca-8,10,12-trienamido)propanoyl)-D-asparaginyl-D-asparagine (1)
(3-((3R,5R,7S,8E,10E,12E)-3-amino-5-hydroxy-7-methoxyoctadeca-8,10,12-trienamido)propanoyl)-D-asparagine (1)
3-((3R,5R,7S,8E,10E,12E)-3-amino-5-hydroxy-7-methoxyoctadeca-8,10,12-trienamido)propanoic acid (1)
(3R,5R,7S,8E,10E,12E)-3-amino-5-hydroxy-7-methoxyoctadeca-8,10,12-trienoic acid (1)

First Public Date

2024 (2)
2017 (2)
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2013 (1)

Study type

Transcription profiling by array (2)
Transcription profiling by SAGE (1)

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2020 (20)
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Lab affiliation

Staff Scientist Biological Systems & Engineering Division Lawrence Berkeley National Laboratory Berkeley CA 94720 (1)

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Mapping the biosynthetic pathway of a hybrid polyketide-nonribosomal peptide in a metazoan

Polyketide synthase (PKS) and nonribosomal peptide synthetase (NRPS) hybrid systems typically use complex protein-protein interactions to facilitate direct transfer of intermediates between these multimodular megaenzymes. In the canal-associated neurons (CANs) of Caenorhabditis elegans, PKS-1 and NR...

2021-06-22 | MTBLS2313 | MetaboLights

Engineering an Extremely Hybrid PKS for Adipic Acid Production

Polyketide synthases (PKSs) are modular enzymes with exceptional potential as biocatalysts for producing non-native compounds. Here, we report the first PKS-based pathway for adipic acid (AA), an industrial monomer for nylon production, by engineering one of the most extensively hybridized PKS syste...

ORGANISM(S): Pseudomonas putida KT2440

2026-09-07 | PXD069956 | Pride