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TranscriptomicsFrom Moderately Severe to Severe Hypertriglyceridemia Induced Acute Pancreatitis: Circulating miRNAs Play Role as Potential Biomarkers
Study the serum miRNA expression profiles in hypertriglyceridemia induced acute pancreatitis and report a possible role of circulating miRNAs as biomarker in the progression of HTAP.
ORGANISM(S): Homo sapiens 
2014-06-05 | E-MTAB-2642 | biostudies-arrayexpress
GenomicsTreatment of genetic screening of hypertriglyceridemia type I, III, and V - HTG Amsterdam

This is a cohort of patients with extreme hypertriglyceridemia. Patients have been screened for loss of function mutations in LPL, GPIHBP1, APOC2, APOA5 and LMF1.

phs000511.v1.p1 | EGA
GenomicsMicroRNA Expression Profiles Analysis in Mouse Pancreatitis Tissue With or Without Hypertriglyceridemia
MicroRNA Expression Profiles Analysis in Mouse Pancreatitis Tissue With or Without Hypertriglyceridemia
PRJNA577036 | ENA
TranscriptomicsThe transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism
Here we report that the transcription factor cyclic AMP–responsive element–binding protein H (CREB-H, encoded by CREB3L3) is required for the maintenance of normal plasma triglyceride concentrations. CREB-H–deficient mice showed hypertriglyceridemia secondary to inefficient triglyceride clearance ca...
ORGANISM(S): Mus musculus 
2011-06-04 | E-GEOD-29643 | biostudies-arrayexpress
GenomicsMicroRNA Expression Profiles Analysis in Mouse Pancreatitis Tissue With or Without Hypertriglyceridemia
The crucial roles of miRNAs have been implicated in various pathological processes, including pancreatitis. However, roles of miRNAs in hypertriglyceridemia-associated pancreatitis have not been reported. Pancreatitis tissue from mice with or without hypertriglyceridemia were analyzed for microRNA p...
ORGANISM(S): Mus musculus 
2022-10-01 | GSE138745 | GEO
GenomicHypertriglyceridemia Study in Mexicans

Coronary artery disease (CAD) is the number one cause of death and mortality world-wide. High levels of serum triglycerides (TGs) and low levels of serum high-density lipoprotein cholesterol (HDL-C) are major risk factors for CAD. Previous epidemiological studies have shown that these two lipid d...

phs000618 | dbGaP
GenomicsDiscovery of Long-Acting APOC3 siRNA for Treating Patients with Hypertriglyceridemia
Discovery of Long-Acting APOC3 siRNA for Treating Patients with Hypertriglyceridemia
PRJNA1167806 | ENA
GenomicsGut Mycobiome Dysbiosis Is Linked to Hypertriglyceridemia among Home Dwelling Elderly Danes
Gut Mycobiome Dysbiosis Is Linked to Hypertriglyceridemia among Home Dwelling Elderly Danes
PRJEB34758 | ENA
GenomicTreatment of Genetic Screening of Hypertriglyceridemia type I, III, and V - HTG Amsterdam

This is a cohort of patients with extreme hypertriglyceridemia. Patients have been screened for loss of function mutations in LPL, GPIHBP1, APOC2, APOA5 and LMF1.

phs000511 | dbGaP
UnknownFamilial hypertriglyceridemia: an entity with distinguishable features from other causes of hypertriglyceridemia.
Not available
S-EPMC7885394 | biostudies-literature
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