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ProteomicsStructural Analysis of 70S Ribosomes by Cross-Linking/Mass Spectrometry Reveals Conformational Plasticity
We analyzed 143 E. coli ribosomal structures, mapping a total of 10,771 intramolecular distances for 126 cross-link-pairs and 3,405 intermolecular distances for 97 protein pairs. Our study might serve as benchmark for conducting biochemical experiments on newly modeled protein regions, guided by XL-...
ORGANISM(S): Escherichia coli 
2020-08-13 | PXD018935 | Pride
Ribosome  cross-linking mass spectrometry 
UnknownUbiquitin binds the amyloid β peptide and interferes with its clearance pathways.
Not available
S-EPMC6419943 | biostudies-literature
ProteomicsComparison of OpenPepXL and xQuest on a Labeled Cross-Linking MS dataset
These data sets are part of a large study aimed at the comparison of experimental and computational workflows used in chemical cross-linking coupled to mass spectrometry. Bovine serum albumin (BSA) was used as a model protein. Two different cross-linking chemistries were used: disuccinimidyl suberat...
ORGANISM(S): Bos taurus (Bovine) 
2020-10-20 | PXD014523 | Pride
Chemical cross-linking  dss  pdh  dmtmm  structural proteomics  bovine serum albumin 
ProteomicsFrom Sea to Therapy: Development and analytical control of recombinant human CDKL5 production in the marine bacterium Pseudoalteromonas haloplanktis TAC125
Marine bacteria are increasingly explored as alternative microbial platforms for the production of high-value biopharmaceuticals, owing to their distinctive physiological and biochemical features. In this study, we focus on the Antarctic marine bacterium Pseudoalteromonas haloplanktis TAC125 (PhTAC1...
ORGANISM(S): Pseudoalteromonas haloplanktis 
2026-05-29 | PXD073800 | Pride
Antarctic marine bacteria  cell-factory  difficult to express proteins  elisa  hcdkl5  protein phosphorylation  pseudoalteromonas haloplanktis tac125  quality by design. 
UnknownAneuploid acute myeloid leukemia exhibits a signature of genomic alterations in the cell cycle and protein degradation machinery.
Not available
S-EPMC6587451 | biostudies-literature
UnknownTargeting WEE1 to enhance conventional therapies for acute lymphoblastic leukemia.
Not available
S-EPMC6090987 | biostudies-literature
UnknownSelf-Reported Non-Celiac Wheat Sensitivity in High School Students: Demographic and Clinical Characteristics.
Not available
S-EPMC5537885 | biostudies-literature
UnknownNew label-free methods for protein relative quantification applied to the investigation of an animal model of Huntington Disease.
Not available
S-EPMC7473538 | biostudies-literature
UnknownStructural analysis of 70S ribosomes by cross-linking/mass spectrometry reveals conformational plasticity.
Not available
S-EPMC7387497 | biostudies-literature
UnknownThe structural principles underlying molybdenum insertase complex assembly.
Not available
S-EPMC10461460 | biostudies-literature
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