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ProteomicsTop Down Proteomic analysis of Gingival Crevicular Fluid in deciduous, exfoliating and permanent teeth in children
Gingival Crevicular Fluid, a plasma-derived exudate present in the gingival crevice was collected from deciduous, exfoliating and permanent teeth from 20 children (60 samples) with the aim to characterize and quantify by a mass spectrometry based top-down proteomic approach, the peptide/proteins in ...
ORGANISM(S): Homo sapiens (Human) 
2020-07-09 | PXD016010 | Pride
Top down Proteomics 
ProteomicsNeutrophil Defensins (Alpha-Defensins)
In the HPLC high-resolution ESI-MS profiles of Gingival Crevicular Fluid, four proteins, with exp. monoisotopic ion [M+H]+ at 3440.54 ± 0.06 m/z, 3369.50± 0.06 m/z, 3484.51 ± 0.06 m/z and 3707.77 ± 0.06, eluting between 24.5-26.6 minutes, were detected. The monoisotopic mass values and the manual in...
ORGANISM(S): Homo sapiens (Human) 
2020-07-09 | PXD016049 | Pride
Gingival crevicular fluid Proteomics Top-down 
ProteomicsExploring the HeLa Dark Mitochondrial proteome
In the framework of the Human Proteome Project initiative, we aim to improve mapping and characterization of mitochondrial proteome. In this work we implemented an experimental workflow, combining classical biochemical enrichments and mass spectrometry, to pursue a much deeper definition of mitochon...
ORGANISM(S): Homo sapiens (Human) 
2020-02-27 | PXD014201 | Pride
Personalised medicine Human mitochondria Dark proteins 
ProteomicsExploring the HeLa Dark Mitochondrial proteome
In the framework of the Human Proteome Project initiative, we aim to improve mapping and characterization of mitochondrial proteome. In this work we implemented an experimental workflow, combining classical biochemical enrichments and mass spectrometry, to pursue a much deeper definition of mitochon...
ORGANISM(S): Homo sapiens (Human) 
2020-02-27 | PXD014200 | Pride
Personalised medicine Subproteome Mass spectrometry Mitochondria Drug targets Dark proteome 
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