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Analysis of ETO2, MYB, EP300 binding as well as H3K27ac, H3K4me1 and H3M27me3 occupancy by ChIP-seq in HEL cells treated with DMSO or dCBP-1 (0.5uM) for 3h or expressing shRNA targeting MYB (shMYB) or genetically inactivated for ETO2 (ETO2ko)
ORGANISM(S): Homo sapiens 
Acute megakaryoblastic leukemia (AMKL) is a heterogeneous disease generally associated with poor prognosis. Gene expression profiles indicate the existence of distinct molecular subgroups and several genetic alterations have been characterized in the past years, including the t(1;22)(p13;q13) and th...
ORGANISM(S): Homo sapiens 
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