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ProteomicsLenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells
Krönke J, Udeshi ND, Narla A, Grauman P, Hurst SN, McConkey M, Svinkina T, Heckl D, Comer E, Li X, Ciarlo C, Hartman E, Munshi N, Schenone M, Schreiber SL, Carr SA, Ebert BL. Science 2014, 343, 301-305. doi:10.1126/science.1244851. Lenalidomide is a drug with clinical efficacy in multiple myeloma an...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-01-26 | MSV000079017 | MassIVE
GenomicsGene expression of B cell and T cell of IKZF3 mutant mice
Gene expression of B cell and T cell of IKZF3 mutant mice
PRJNA982683 | ENA
GenomicsA hotspot mutation p.L162R in IKZF3 drives leukemogenesis via transcriptional dysregulation
A hotspot mutation p.L162R in IKZF3 drives leukemogenesis via transcriptional dysregulation
PRJNA601427 | ENA
TranscriptomicsGene expression of B cell and T cell of IKZF3 mutant mice
To identify genes dysregulated by Aiolos N159S variant, splenic B cell and T cell populations of Ikzf3 +/+, Ikzf3 +/N159S and Ikzf3 N159S/N159S mice were subjected to RNA-seq analyses.
ORGANISM(S): Mus musculus 
2023-08-02 | GSE234649 | GEO
UnknownIKZF3 amplification predicts worse prognosis especially in intestinal-type gastric cancer.
Not available
S-EPMC11272681 | biostudies-literature
UnknownBaicalein Inhibits Proliferation of Myeloma U266 Cells by Downregulating IKZF1 and IKZF3.
Not available
S-EPMC5958785 | biostudies-literature
UnknownA hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation.
Not available
S-EPMC8034546 | biostudies-literature
UnknownAllelic imbalance of multiple sclerosis susceptibility genes IKZF3 and IQGAP1 in human peripheral blood.
Not available
S-EPMC4832550 | biostudies-literature
UnknownAssociation between polymorphisms of the IKZF3 gene and systemic lupus erythematosus in a Chinese Han population.
Not available
S-EPMC4182708 | biostudies-literature
UnknownNovel IKZF3 transcriptomic signature correlates with positive outcomes of skin cutaneous melanoma: A pan-cancer analysis.
Not available
S-EPMC9638148 | biostudies-literature
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