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TranscriptomicsGene Expression Effects of IL-13 on Primary Human Airway Epithelial Cells
Primary culture airway epithelial cells, grown under physiologic air-liquid interface conditions, with, or without IL-13 in order to study the effects of this cytokine on mucous cell metaplasia, an important feature of asthma and COPD. Keywords: IL13, mucus, goblet cell RNA was isolated from primary...
ORGANISM(S): Homo sapiens 
2012-12-04 | E-GEOD-37693 | biostudies-arrayexpress
TranscriptomicsIL-13 Stimulated Esophageal Epithelial miRNA
miRNA profiling of unstimulated and IL-13 stimulated esophageal epithelial cells
ORGANISM(S): Homo sapiens 
2012-06-26 | E-MEXP-3351 | biostudies-arrayexpress
TranscriptomicsIL-13 miR-375 Esophageal Epithelial Cell
Expression profiling of Control transduced and Pre-miR-375 transduced esophageal epithelial cells stimulated with or without IL-13
ORGANISM(S): Homo sapiens 
2012-06-27 | E-MEXP-3345 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human eosinophilic esophagitis biopsies, cultured and stimulated with IL-13
3 eosinophilic esophagitis biopsies, cultured and stimulated with IL-13 : each of them was either left unstimulated or stimulated (100ng for 48h); We used microarray to uncover the IL-13-induced genes in esophageal epithelial cells of the esophagus Experiment Overall Design: 3 biopsies from EE patie...
ORGANISM(S): Homo sapiens 
2008-06-20 | E-GEOD-8853 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human bronchial epithelial cells stimulated with IL-13
Human bronchial epithelial cells were stimulated without or with 100 ng/mL IL-13 for 24 hours.
ORGANISM(S): Homo sapiens 
2012-07-05 | E-MEXP-3353 | biostudies-arrayexpress
TranscriptomicsRNAseq of small intestinal organoids from mice treated with the cytokines IL-13 and IL-22 for 72 hours in combination with the BMP signaling inhibitor DMH1
The intestinal epithelium is our first line of defense against infections of the gut and the plasticity in cellular differentiation of the intestinal epithelium is an important part of this response. The changes in cellular composition is driven by immune cell derived cytokines. Here we use signatur...
ORGANISM(S): Mus musculus 
2022-05-08 | E-MTAB-9185 | biostudies-arrayexpress
TranscriptomicsHigh salt reduces the activation of IL-4+IL-13 stimulated macrophages
High salt (NaCl) intake is a major risk factor for cardiovascular disease; high NaCl has also been shown to be a powerful modulator of pro-inflammatory immune cell polarization. To investigate the effect of high NaCl on the polarization of M(IL-4+IL-13) macrophages we performed gene expression analy...
ORGANISM(S): Mus musculus 
2014-12-16 | E-MTAB-3163 | biostudies-arrayexpress
GenomicsHigh salt reduces the activation of IL-4+IL-13 stimulated macrophages
High salt (NaCl) intake is a major risk factor for cardiovascular disease; high NaCl has also been shown to be a powerful modulator of pro-inflammatory immune cell polarization. To investigate the effect of high NaCl on the polarization of M(IL-4+IL-13) macrophages we performed gene expression analy...
ORGANISM(S): Mus musculus 
2015-02-07 | E-MTAB-3140 | biostudies-arrayexpress
GenomicsNeurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation
Despite the well-recognized role of IL-13–induced transcriptional responses in allergic inflammation, the epigenetic mechanisms driven by IL-13 have not been well defined. We interrogated the transcriptional and epigenetic signatures of IL-13-induced epithelial responses focusing on the chromatin ac...
ORGANISM(S): Homo sapiens 
2015-04-09 | E-GEOD-57637 | biostudies-arrayexpress
TranscriptomicsExpression profiling of IL-13 stimulated PBMCs with and without an IL-13R antagonist
This experiment aims to identify the biological pathways and diseases associated with the cytokine Interleukin 13 (IL-13) using gene expression measured in peripheral blood mononuclear cells (PBMCs). The experiment comprised of samples obtained from 3 healthy donors. The expression profiles of in vi...
ORGANISM(S): Homo sapiens 
2016-03-10 | E-GEOD-79027 | biostudies-arrayexpress
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