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GenomicsIL-1 protects from fatal systemic candidiasis by inhibition of oxidative phosphorylation and hypoxia [snRNA-Seq]
IL-1 protects from fatal systemic candidiasis by inhibition of oxidative phosphorylation and hypoxia [snRNA-Seq]
PRJNA1190429 | ENA
GenomicsIL-1 protects from fatal systemic candidiasis by inhibition of oxidative phosphorylation and hypoxia [bulk RNA-Seq]
IL-1 protects from fatal systemic candidiasis by inhibition of oxidative phosphorylation and hypoxia [bulk RNA-Seq]
PRJNA1190427 | ENA
UnknownShort cytoplasmic isoform of IL1R1/CD121a mediates IL1β induced proliferation of synovium-derived mesenchymal stem/stromal cells through ERK1/2 pathway.
Not available
S-EPMC9133583 | biostudies-literature
TranscriptomicsIL-1 protects from fatal systemic candidiasis by inhibition of oxidative phosphorylation and hypoxia [snRNA-Seq]
Invasive C. albicans infections result in high mortality rates. While IL-1 is important to combat these infections, the precise mode of action remains unclear. Using global and conditional Il1r1 knockouts in mice, we found that IL-1R-signaling in non-hematopoietic cells in the kidney and brain is cr...
ORGANISM(S): Mus musculus 
2025-02-20 | GSE282797 | GEO
TranscriptomicsIL-1 protects from fatal systemic candidiasis by inhibition of oxidative phosphorylation and hypoxia [bulk RNA-Seq]
Invasive C. albicans infections result in high mortality rates. While IL-1 is important to combat these infections, the precise mode of action remains unclear. Using global and conditional Il1r1 knockouts in mice, we found that IL-1R-signaling in non-hematopoietic cells in the kidney and brain is cr...
ORGANISM(S): Mus musculus 
2025-02-20 | GSE282796 | GEO
UnknownIL-1 protects from fatal systemic candidiasis in mice by inhibiting oxidative phosphorylation and hypoxia.
Not available
S-EPMC11914259 | biostudies-literature
UnknownBLK positively regulates TLR/IL-1R signaling by catalyzing TOLLIP phosphorylation.
Not available
S-EPMC10711807 | biostudies-literature
TranscriptomicsHuman skin fibroblast mitochondrial depletion, 0.5 Gy alpha-particle
Mitochondrial DNA-depleted human skin fibroblasts (HSF rho0) with suppressed oxidative phosphorylation were characterized by significant changes in the expression of 2100 nuclear genes, encoding numerous protein classes, in NF-kappaB and STAT3 signaling pathways and by decreased activity of the mito...
ORGANISM(S): Homo sapiens 
2011-04-04 | E-GEOD-24945 | biostudies-arrayexpress
TranscriptomicsMacrophage-derived IL-1β controls metabolic reprograming in distinct fibroblast progenitors to determine cell fate during wound healing
Compare with facial skin, oral mucosa has a high regenerative capacity and rapid healing efficiency, which has long been recognized as an ideal system of wound resolution. To decipher the underlying molecular mechanisms fostering this optimal healing process, we created a parallel injury model for b...
ORGANISM(S): Mus musculus 
2025-09-03 | GSE256125 | GEO
UnknownIdentification of Interleukin-1 by Functional Screening as a Key Mediator of Cellular Expansion and Disease Progression in Acute Myeloid Leukemia.
Not available
S-EPMC5437102 | biostudies-literature
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