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TranscriptomicsMicroRNA (miRNA) expression of IMCD tubule suspension
miRNA plays a role as post-transcriptional regulator. However, miRNAs in the kidney collecting duct cell have not been well understood. So we aimed to profile miRNAs in the kidney inner medullary collecting duct (IMCD) cells, and to identify the vasopressin-responsive miRNAs in the kidney IMCD cells...
ORGANISM(S): Rattus norvegicus 
2014-06-21 | E-GEOD-58693 | biostudies-arrayexpress
ProteomicsComprehensive Proteomic Profiling of Nuclear Fractions from Native Renal Inner Medullary Collecting Duct Cells
Regulation of renal water excretion is dependent on control of the molecular water channel aquaporin‐2 by the peptide hormone vasopressin in renal collecting duct cells. The control is in part due to the regulation of transcription of the Aqp2 gene and other genes by vasopressin. A systems biology‐b...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-10-24 | PXD002680 | Pride
Transcription Transcription factor Kidney Lc‐ms/ms Chromatin Mrna splicing 
TranscriptomicsTranscription profiling of rat inner medullary collecting duct
Identification of gene expressed in the enriched inner medullary collecting duct cells in rat. Experiment Overall Design: Rat inner medullary collecting duct (IMCD) cells were isolated from 7 male Sprage-Dawley rats by collagenase and hyaluronidase digestion and follow by low speed centrifugation. T...
ORGANISM(S): Rattus norvegicus 
2008-06-15 | E-GEOD-7891 | biostudies-arrayexpress
UnknownGenetic basis for iMCD-TAFRO.
Not available
S-EPMC7148173 | biostudies-literature
GenomicsMicroRNA (miRNA) expression of IMCD tubule suspension
miRNA plays a role as post-transcriptional regulator. However, miRNAs in the kidney collecting duct cell have not been well understood. So we aimed to profile miRNAs in the kidney inner medullary collecting duct (IMCD) cells, and to identify the vasopressin-responsive miRNAs in the kidney IMCD cells...
ORGANISM(S): Rattus norvegicus synthetic construct 
2014-06-21 | GSE58693 | GEO
ProteomicsIdentification of β-Catenin-Interacting Proteins in Nuclei of Aquaporin-2-Expressing Rat Collecting Duct Cells
The gene encoding the aquaporin-2 water channel is regulated transcriptionally in response to vasopressin. In the renal collecting duct, vasopressin stimulates the nuclear translocation and phosphorylation (at Ser552) of β-catenin, a multifunctional protein that can act as a transcriptional co-regul...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-10-26 | PXD005792 | Pride
Transcription Transcriptional co-regulator Aquaporin-2 Kidney 
UnknownInhibition of Pkhd1 impairs tubulomorphogenesis of cultured IMCD cells.
Not available
S-EPMC1196347 | biostudies-literature
TranscriptomicsOsmolality as a major regulator of the transcriptome and metabolome in kidney collecting duct cells
We hypothesized that altered extracellular osmolality per se could affect the transcriptome of the kidney inner medullary collecting duct (IMCD) cells, and hence it might change renal tubular function. The data sets of transcriptomics were incorporated into the "omic" data sets of metabolo...
ORGANISM(S): Rattus norvegicus 
2012-02-09 | E-GEOD-35598 | biostudies-arrayexpress
UnknownUnexpected localization of AQP3 and AQP4 induced by migration of primary cultured IMCD cells.
Not available
S-EPMC8185088 | biostudies-literature
GenomicsRattus norvegicus
MicroRNA (miRNA) expression of IMCD tubule suspension
PRJNA253188 | ENA
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