Immune-escape - OmicsDI

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CHEBI ID

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CHEBI:75461 (1)
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CHEBI:16112|CHEBI:16384|CHEBI:75489|CHEBI:75491 (1)
CHEBI:1945|CHEBI:75499|CHEBI:75500 (1)
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CHEBI:75438 (1)
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CHEBI:75554 (1)
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CHEBI:75520 (1)
CHEBI:75518|CHEBI:18330 (1)
CHEBI:75516|unknown (1)
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CHEBI:75493|CHEBI:75496|CHEBI:75497 (1)
CHEBI:75467 (1)
CHEBI:75428 (1)
CHEBI:75368 (1)
CHEBI:75413 (1)
CHEBI:75398 (1)
CHEBI:75396 (1)
CHEBI:75395 (1)
CHEBI:75386 (1)
CHEBI:75420 (1)
CHEBI:75349|CHEBI:75353 (1)
CHEBI:75440 (1)
CHEBI:75435 (1)
CHEBI:16034 (1)

Metabolite Name

Uric acid (3)
3,5-Dimethyl-3'-isopropyl-L-thyronine (2)
5-Methyltetrahydrofolic acid (2)
Pantetheine 4'-phosphate (2)
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Spermidine (2)
Guanine (2)
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PppGpp (1)
PA(14:0/6 keto-PGF1alpha) (1)

First Public Date

2024 (119)
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2014 (24)
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Modelling Approach

Ordinary differential equation model (11)

Study status

Completed (3)
Recruiting (1)

Lab affiliation

Department of Chemistry, King’s College London, SE1 1DB, London, UK Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, M13 9PT, Manchester, UK Manchester Institute of Biotechnology, The University of Manchester, M1 7DN, Manchester, UK (2)
First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China (2)
Department of Molecular Pathology and Biology, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic (2)
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Karolinska Institutet, Department of Medicine Solna, Unit of Translational Immunology (1)
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Personalis Inc., Menlo Park, USA. (1)
Institut Pasteur, Université Paris-Cité, CNRS, UAR 2024, Mass Spectrometry for Biology, 75015 PARIS (1)
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Sir Peter MacCallum Department of Oncology, Peter MacCallum Cancer Centre, The University of Melbourne, Victoria 3000, Australia (1)
Department of Innovative Technologies in Medicine & Dentistry, University of "G. d'Annunzio" of Chieti-Pescara, Chieti, Italy (1)
sichuan university (1)
Division of Oncogenomics, Oncode institute, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands; (1)
Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands (1)
Division of Immunotherapy and Immunoprevention, German Cancer Research Center (DKFZ), Heidelberg, Germany (1)
Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU), School of Life Sciences, University of Dundee, Dundee, UK (1)
Center for Biomedical Mass Spectrometry, Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, United States of America (1)
Civil Aviation Medicine Center, Civil Aviation Administration of China (1)
Center for neuroscience and cell biology (1)
MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China. (1)
Université Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Jouy-en-Josas, France (1)
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Department of Biochemistry and Molecular Biology, Rutgers University, Robert Wood Johnson Medical School, USA (1)
Cancer Research Center, School of Medicine, Xiamen University (1)
Faculty of Medicine, Institute of Biochemistry II, Goethe University, 60590 Frankfurt am Main, Germany. Frankfurt Cancer Institute, Goethe University, 60596 Frankfurt am Main, Germany. Cardio-Pulmonary Institute, Goethe University, 60590 Frankfurt am Main, Germany (1)
Université de Strasbourg, CNRS, Architecture et Réactivité de l’ARN, UPR9002, Strasbourg, France (1)
Department of Biology, Univ. Lille, Inserm, CHU Lille, U1192-Protéomique Réponse Inflammatoire Spectrométrie de Masse-PRISM,, Lille, FR (1)
Yale System Biology Institute, Yale Department of Genetics, Yale Center for Cancer Systems Biology (1)
Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, P.R. China (1)

Keyword

Immune checkpoints (2)
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T cell (1)
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False (12)

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Palmitic Acid-Triggerd B7H3 Palmitoylation Promotes Immune Escape

B7H3 (CD276), a key immune checkpoint molecule that is overexpressed in tumors, plays a central role in cancer progression, making it a highly promising and specific therapeutic target. Here, we discovered that the cellular metabolite palmitic acid contributes to the development of an immunosuppr...

2025-12-03 | MTBLS12300 | MetaboLights

Glioma escape signature and clonal development under immune pressure [microarray]

PRJNA635387 | ENA

Glioma escape signature and clonal development under immune pressure [RNA-Seq]

PRJNA635388 | ENA

The EVI5 oncogene drives tumor immune escape by regulating PD-L1 in Lung Adenocarcinoma

Ecotropic viral integration site 5 (EVI5), a member of the Tre-2/Bub2/Cdc16 (TBC) domain-containing protein family, has been implicated in the initiation of various cancers. However, its precise role in lung adenocarcinoma (LUAD) remains unclear. This study investigated the pro-tumoral role of EVI5 ...

ORGANISM(S): Homo Sapiens

PXD064761 |

GAS6 drives chemoresistance and immune escape in ovarian cancer

PRJNA1503588 | ENA

Ubiquitin-activating enzyme mediates immune escape via suppressing interferon signaling

PRJNA1067613 | ENA

Retroviral transduction of NOTCH1 into primary human Chronic Lymphocytic Leukemia cells unravels immune escape-mechanisms

Functional studies to investigate gene mutations recurrent in B cell lymphoma have been hampered by the inability to genetically manipulate primary cells, attributed to low transduction efficacy and procedure-associated toxicity. Alternative approaches utilize cell lines and mouse models, which ofte...

ORGANISM(S): Homo sapiens (Human)

2022-08-26 | PXD024112 | Pride

Spatiotemporal evolution of the ccRCC microenvironment links intra-tumoral heterogeneity to immune escape CINOMA

PRJNA888194 | ENA

Spatiotemporal evolution of the ccRCC microenvironment links intra-tumoral heterogeneity to immune escape CINOMA

PRJNA888195 | ENA

ALDH1A1 Promotes Immune Escape of Tumor Cells through ZBTB7B-Glycolysis Pathway

PRJNA1124139 | ENA

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