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MetabolomicsMetabolic interactions of “catecholamine-cholesterol derivatives” as a potential mechanism for immunomodulation of chicken adipose tissue

In recent years, the immunomodulatory function of adipose tissue has attracted much attention; however, the mechanism of steady-state regulation of the immune microenvironment in adipose tissue remains unclear. Catecholamines (CAs) activate adipocyte surface β3-AR to promote lipid metabolism, and...

2025-07-15 | MTBLS12719 | MetaboLights
TranscriptomicsDose-dependent immunomodulation of human dendritic cells by the probiotic Lactobacillus rhamnosus Lcr35
Gene expression changes in human dendritic cells after contact with either 10e4 or 10e7 CFU of Lactobacillus rhamnosus Lcr35 Bacterial cells were incubated for 3 hours with dendritic cells. Total RNA was extracted, quantified, and labeled with Cy3 or Cy5 (control, dendritic cells without bacteria). ...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-25699 | biostudies-arrayexpress
UnknownCoinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.
Not available
S-EPMC4548887 | biostudies-literature
GenomicsProgesterone promotes immunomodulation and tumor development in the murine mammary gland
Progesterone promotes immunomodulation and tumor development in the murine mammary gland
PRJNA664102 | ENA
UnknownTranscriptional changes in the Japanese scallop (Mizuhopecten yessoensis) shellinfested by Polydora provide insights into the molecular mechanism of shell formation and immunomodulation.
Not available
S-EPMC6281612 | biostudies-literature
GenomicsRegulating Interleukin-2 activity with engineered receptor signaling clamps
Interleukin-2 (IL-2) is a pleiotropic cytokine that regulates lymphocyte function by signaling through heterodimerization of the IL-2Rβ and γc receptor subunits. Previously, we engineered an IL-2 “superkine” (H9) with enhanced affinity for IL-2Rβ. Here, we describe next-generation IL-2 variants that...
ORGANISM(S): Homo sapiens 
2015-06-16 | E-GEOD-64713 | biostudies-arrayexpress
UnknownSelenium Nanoparticles (SeNPs) Immunomodulation Is More Than Redox Improvement: Serum Proteomics and Transcriptomic Analyses.
Not available
S-EPMC9137598 | biostudies-literature
UnknownComprehensive Molecular Profiles of Functionally Effective MSC-Derived Extracellular Vesicles in Immunomodulation.
Not available
S-EPMC7335740 | biostudies-literature
TranscriptomicsGene expression profiling of dendritic cells in different physiological stages under Cordyceps sinensis treatment
Cordyceps sinensis (CS) has been commonly used as a herbal medicine as well as a health supplement in China for over two thousand years. Although previous studies demonstrated that CS has benefit in immunoregulation and anti-inflammation, the precise mechanism by which CS affects immunomodulation is...
ORGANISM(S): Homo sapiens 
2011-09-08 | E-GEOD-24191 | biostudies-arrayexpress
UnknownBordetella filamentous hemagglutinin plays a critical role in immunomodulation, suggesting a mechanism for host specificity.
Not available
S-EPMC1317942 | biostudies-literature
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