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TranscriptomicsmicroRNAs as predictive biomarkers of response to sunitinib or pazopanib in patients with metastatic renal cell carcinoma
The aim of the experiment was to discover differentially expressed miRNAs correlating with prolonged response to targeted therapy in patients with metastatic renal cell carcinoma treated with sunitinib or pazopanib
ORGANISM(S): Homo sapiens 
2018-02-08 | E-MTAB-6296 | biostudies-arrayexpress
UnknownCirculating regulatory T cells predict efficacy and atypical responses in lung cancer patients treated with PD-1/PD-L1 inhibitors.
Not available
S-EPMC8854239 | biostudies-literature
TranscriptomicsCheckpoint blockade immunotherapy relies on T-bet but not Eomes to induce effector function in tumor infiltrating CD8+ T cells
Coinhibitory receptor blockade is a promising strategy to boost immunity against a variety of human cancers. However, many patients still do not benefit from this treatment, and responders often experience immune-related toxicities. These issues highlight the need for improved understanding of check...
ORGANISM(S): Mus musculus 
2014-12-18 | E-GEOD-58722 | biostudies-arrayexpress
UnknownCancer-targeted photoimmunotherapy induces antitumor immunity and can be augmented by anti-PD-1 therapy for durable anticancer responses in an immunologically active murine tumor model.
Not available
S-EPMC9813181 | biostudies-literature
UnknownAdoptive T cell therapy combined with intralesional administrations of TG1042 (adenovirus expressing interferon-γ) in metastatic melanoma patients.
Not available
S-EPMC11029588 | biostudies-literature
UnknownImmune Mechanisms and Pathways Targeted in Type 1 Diabetes.
Not available
S-EPMC8053389 | biostudies-literature
UnknownA Plasma miR-193b-365 Signature Combined With Age and Glycemic Status Predicts Response to Lactococcus lactis-Based Antigen-Specific Immunotherapy in New-Onset Type 1 Diabetes.
Not available
S-EPMC10545562 | biostudies-literature
UnknownCombinational expression of tumor testis antigens NY-ESO-1, MAGE-A3, and MAGE-A4 predicts response to immunotherapy in mucosal melanoma patients.
Not available
S-EPMC10356647 | biostudies-literature
UnknownRationally targeted anti-VISTA antibody that blockades the C-C' loop region can reverse VISTA immune suppression and remodel the immune microenvironment to potently inhibit tumor growth in an Fc independent manner.
Not available
S-EPMC8823246 | biostudies-literature
TranscriptomicsGene expression analysis in adoptive T cell immunotherapy (ACT)
To understand the global effector immune responses in the tumor induced by ACT, we performed a gene chip analysis using B16 melanoma-pmel-1 TCR transgenic T cells model. Gene expression was measured in the tumor from untreated or ACT mice on day 1, 3, 5 and 7. Gene expression was also measured in th...
ORGANISM(S): Mus musculus 
2014-08-25 | E-GEOD-57304 | biostudies-arrayexpress
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