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TranscriptomicsRNAi knock down of RNA binding IMP proteins in human epithelial (HeLa) cells
To identify factors and pathways regulated by IMP proteins and obtain leads to the mechanism behind the phenotypic changes, we compared the gene expression profiles of IMP siRNA treated cells with mock treated cells. Triplicate gene expression profiles were generated from both the IMP(1,3)A and IMP(...
ORGANISM(S): Homo sapiens 
2006-09-30 | E-MEXP-548 | biostudies-arrayexpress
TranscriptomicsThe let-7-Imp axis regulates aging of the Drosophila testis stem cell niche.
Adult stem cells support tissue homeostasis and repair throughout the life of an individual. However, numerous intrinsic and extrinsic changes occur with age that result in altered stem cell behavior and reduced tissue maintenance and regeneration. In the Drosophila testis, stem cells surround and c...
ORGANISM(S): Drosophila melanogaster 
2012-05-31 | E-GEOD-37041 | biostudies-arrayexpress
TranscriptomicsDrosophila Imp iCLIP identifies an RNA assemblage co-ordinating F-actin formation
In this study, we employed a combination of RIP-seq and short- and long-wave iCLIP technologies to identify transcripts associated with cytoplasmic RNPs containing the RNA-binding protein Drosophila Imp. We also made a Imp knockdown vs luciferase control experiment. Two biological iCLIP-seq, as well...
ORGANISM(S): Drosophila melanogaster 
2015-05-27 | E-GEOD-62997 | biostudies-arrayexpress
TranscriptomicsMeWo/IMP-3 v.s. MeWo/vec
IMP-3 Promotes Migration and Invasion of Melanoma Cells by Modulating the Expression of HMGA2 and Predicts Poor Prognosis in Melanoma Two-condition experiment,MeWo/IMP-3 v.s. MeWo/vec. Biological replicates: 2 control replicates, 2 transfected replicates.
ORGANISM(S): Homo sapiens 
2014-10-23 | E-GEOD-62574 | biostudies-arrayexpress
TranscriptomicsGenerating mouse model with predominant naïve or innate memory phenotype CD4+ T cells
Innate memory phenotype (IMP) CD4+ T cells are non-conventional αβ T cells exhibiting features of innate immune cells, characterized as CD44high and CD62Llow in periphery. It is recently reported by our group that bone marrow chimeric mice lacking thymic MHCI expression develop predominantly IMP C...
ORGANISM(S): Mus musculus 
2014-03-14 | E-GEOD-46892 | biostudies-arrayexpress
GenomicsPseudomonas aeruginosa strain:IMP-13
Pseudomonas aeruginosa strain:IMP-13 Genome sequencing
PRJNA507737 | ENA
GenomicsIMP-producing Pseudomonas aeruginosa
IMP-producing Pseudomonas aeruginosa
PRJEB53622 | ENA
TranscriptomicsChromatin immunoprecipitation of human HEK293 cells with flag-tagged IMP1 antibody
Isolation of IMP1 bound mRNAs. Flag-tagged IMP1 was expressed in HEK293 cells. Flag tagged IMP1 was immunoprecipitated and mRNAs isolated. As controls HEK293 cells that do not express Flag-tagged IMP1 was included.
ORGANISM(S): Homo sapiens 
2006-12-31 | E-MEXP-841 | biostudies-arrayexpress
GenomicsImidazole propionate (ImP): effect on human aortic endothelial cells
Imidazole propionate (ImP): effect on human aortic endothelial cells
PRJEB61803 | ENA
TranscriptomicsDistinguishing innate memory CD8+ T from homeostatically expanded CD8+ T cells
Innate memory phenotype (IMP) CD8+ T cells are non-conventional αβ T cells exhibiting features of innate immune cells, and are significantly increased in the absence of non-receptor tyrosine kinase ITK. Their developmental path and function are not clear, particularly whether they can contribute to ...
ORGANISM(S): Mus musculus 
2013-02-19 | E-GEOD-41482 | biostudies-arrayexpress
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