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UnknownENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in cystic fibrosis.
Not available
S-EPMC6764826 | biostudies-literature
GenomicsCurcumin Attenuates Liver Fibrosis and Inflammation by Modulating Slamf8-Mediated TNF/NF-κB Signaling
Curcumin Attenuates Liver Fibrosis and Inflammation by Modulating Slamf8-Mediated TNF/NF-κB Signaling
PRJNA1274890 | ENA
ProteomicsUnraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of Pseudomonas aeruginosa in an organotypic 3-D lung epithelial cell model
Pseudomonas aeruginosa chronically infects the lungs of people with cystic fibrosis (pwCF), where it produces a broad range of proteases that impact host immunity and inflammation. While some studies suggest these enzymes induce inflammation and may contribute to the excessive inflammatory response ...
ORGANISM(S): Homo sapiens (Human) Pseudomonas aeruginosa PAO1 
2025-10-23 | PXD065321 | Pride
Cystic fibrosis Proteomics Inflammation Elastase b Pseudomonas aeruginosa Bacterial proteases Virulence factors 
TranscriptomicsGene Expression in Biopsies of Acute Rejection and Interstitial Fibrosis/Tubular Atrophy Reveals Highly Shared Mechanisms that Correlate with Worse Long-term Outcomes
Rationale: Interstitial fibrosis and tubular atrophy (IFTA) is found in ~25% of 1-year biopsies post-transplant(1, 2). It correlates with decreased graft survival when histological evidence of inflammation is present¬.(3-5) Identifying the etiology of IFTA is important because longterm graft surviva...
ORGANISM(S): Homo sapiens 
2016-01-15 | E-GEOD-76882 | biostudies-arrayexpress
UnknownGSDME-mediated pyroptosis promotes inflammation and fibrosis in obstructive nephropathy.
Not available
S-EPMC8329275 | biostudies-literature
GenomicsSalvianolic acid B attenuates inflammation and prevent pathologic fibrosis by inhibiting CD36-mediated activation of the PI3K-Akt signaling pathway in frozen shoulder [dataset 1]
Salvianolic acid B attenuates inflammation and prevent pathologic fibrosis by inhibiting CD36-mediated activation of the PI3K-Akt signaling pathway in frozen shoulder [dataset 1]
PRJNA997890 | ENA
GenomicsSalvianolic acid B attenuates inflammation and prevent pathologic fibrosis by inhibiting CD36-mediated activation of the PI3K-Akt signaling pathway in frozen shoulder [dataset 2]
Salvianolic acid B attenuates inflammation and prevent pathologic fibrosis by inhibiting CD36-mediated activation of the PI3K-Akt signaling pathway in frozen shoulder [dataset 2]
PRJNA997891 | ENA
GenomicsExcessive adventitial stress drives inflammation-mediated fibrosis in hypertensive aortic remodelling in mice
Excessive adventitial stress drives inflammation-mediated fibrosis in hypertensive aortic remodelling in mice
PRJNA1173561 | ENA
UnknownResolvin D1 Reduces Lung Infection and Inflammation Activating Resolution in Cystic Fibrosis.
Not available
S-EPMC7247852 | biostudies-literature
TranscriptomicsGlobal gene expression profile of small intestine from wild-type and CFTR-knockout mice.
The objective of this study was to identify changes in gene expression levels between wild-type and CFTR-knockout small intestine. CFTR-knockout mice (provided by Dr. Lane Clarke of the University of Missouri) were maintained on colyte. Keywords: gene expression comparison Four wild-type and four C...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-8763 | biostudies-arrayexpress
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