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MetabolomicsMulti-omic analysis of vaginal bacteria:host immune and metabolic interactions in early adverse pregnancy outcomes

Objective

To characterise the vaginal microbiota, mucosal metabolome and host immune response in early pregnancy and investigate its relationship with adverse pregnancy outcomes, including ectopic pregnancy, within the context of pregnancies of unknown location (PUL).

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2025-03-28 | MTBLS10098 | MetaboLights
UnknownA Multimodal Imaging Approach Demonstrates Reduced Midbrain Functional Network Connectivity Is Associated With Freezing of Gait in Parkinson's Disease.
Not available
S-EPMC8120105 | biostudies-literature
UnknownUpdated distribution of the invasive Megachile sculpturalis (Hymenoptera: Megachilidae) in Italy and its first record on a Mediterranean island.
Not available
S-EPMC7714772 | biostudies-literature
UnknownA hnRNP K⁻AR-Related Signature Reflects Progression toward Castration-Resistant Prostate Cancer.
Not available
S-EPMC6073607 | biostudies-literature
ProteomicsPhenotypic quantitative high throughput screening with Caenorhabditis elegans
Quantitative high throughput screening (qHTS) pharmacologically evaluates libraries of drugs and investigational agents for potential therapeutic uses, toxicological risk assessment, and increasingly for academic chemical tool discovery. Phenotypic HTS assays aim to interrogate molecular pathways a...
ORGANISM(S): Caenorhabditis elegans 
2023-05-30 | PXD027733 | Pride
Model organisms Laser cytometry Drug discovery Infectious disease Genetic disorders High-throughput screening 
MetabolomicsDirect on-swab metabolic profiling of vaginal microbiome:host interactions during pregnancy and preterm birth

The pregnancy vaginal microbiome contributes to risk of preterm birth, the primary cause of death in children under 5 years of age. Here we describe direct on-swab metabolic profiling by Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) for sample preparation-free characterisation of...

2021-09-23 | MTBLS717 | MetaboLights
UnknownTissue factor as a potential coagulative/vascular marker in relapsing-remitting multiple sclerosis.
Not available
S-EPMC10424925 | biostudies-literature
ProteomicsPharmacoproteomic profiling directed by C. elegans-driven phenotypic quantitative HTS
Quantitative high-throughput screening (qHTS) pharmacologically evaluates libraries of drugs and investigational agents for potential therapeutic uses, toxicological risk assessment, and increasingly for academic chemical tool discovery. Phenotypic HTS assays aim to interrogate molecular pathways a...
ORGANISM(S): Caenorhabditis elegans 
2023-02-21 | PXD033552 | Pride
Model organisms Laser cytometry Proteomics Drug discovery Infectious disease Genetic disorders High-throughput screening 
UnknownPerspectives on Neuromyelitis Optica Spectrum Disorders, the Narrative Medicine contribution to care.
Not available
S-EPMC10942930 | biostudies-literature
UnknownZoledronic acid boosts γδ T-cell activity in children receiving αβ+ T and CD19+ cell-depleted grafts from an HLA-haplo-identical donor.
Not available
S-EPMC5353934 | biostudies-literature
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