Sort   by:  
 Page size 
MetabolomicsApolipophorin-III modulates antiviral defense in Bombyx mori: an integrated transcriptomic and lipidomic analysis of its inhibitory role against BmNPV infection.

The silkworm (Bombyx mori) is an economically important insect and a lepidopteran model organism. Controlling viral infections is crucial for the sustainable development of sericulture. Bombyx mori nucleopolyhedrovirus (BmNPV) infection can cause large-scale mortality in silkworm populations. Ins...

2025-12-03 | MTBLS13447 | MetaboLights
TranscriptomicsTLR 4 Signaling Inhibitory Pathway Induced by Green Tea Polyphenol Epigallocatechin-3-Gallate through 67-kDa Laminin Receptor
Epigallocatechin-3-gallate (EGCG), a major active polyphenol of green tea, has been shown to downregulate inflammatory responses in macrophages; however, the underlying mechanism has not been understood. Recently, we identified the 67-kDa laminin receptor (67LR) as a cell-surface EGCG receptor that ...
ORGANISM(S): Mus musculus 
2010-04-20 | E-GEOD-21320 | biostudies-arrayexpress
TranscriptomicsLeukemia Inhibitory Factor in C26 Cancer Cachexia
Cachexia is an exacerbating event in many types of cancer that is strongly associated with a poor prognosis. We have identified cytokine, signaling and transcription factors that are required for cachexia in the mouse C26 colon carcinoma model of cancer. C2C12 myotubes treated with conditioned mediu...
ORGANISM(S): Mus musculus 
2015-06-25 | E-GEOD-68827 | biostudies-arrayexpress
GenomicsThe inhibitory receptor CD200R educates ILC1s for optimal cytotoxicity
The inhibitory receptor CD200R educates ILC1s for optimal cytotoxicity
PRJNA1321790 | ENA
TranscriptomicsTranscriptional profiling of LIF stimulation in mouse embryonic stem cells
Stat3+/+ and -/- ES cells were cultured in defined conditions and exposed to leukemia inhibitory factor (LIF) in a 24h timecourse to identify Stat3-independent targets of the self-renewal response to LIF signaling.
ORGANISM(S): Mus musculus 
2013-08-01 | E-MTAB-1796 | biostudies-arrayexpress
TranscriptomicsA chemical genetic approach identifies piperazine antipsychotics as promoters of CNS neurite growth on inhibitory substrates.
Injury to the central nervous system (CNS) may result in lifelong loss of function due, in part, to the regenerative failure of CNS neurons. Major barriers to regeneration faced by injured CNS neurons include inhibitory proteins derived from myelin and the astroglial scar. Previously, we described...
ORGANISM(S): Homo sapiens 
2012-04-29 | E-GEOD-34331 | biostudies-arrayexpress
TranscriptomicsCXCR3+ Treg cells suppress Th1-immune responses through expression of the co-inhibitory receptors CD85k and Lag-3
CD4+Foxp3+ Treg cells are essential for maintaining self-tolerance and preventing excessive immune responses. In the context of Th1 immune responses, co-expression of the Th1 transcription factor T-bet with Foxp3 is essential for Treg cells to control Th1 responses. T-bet-dependent expression of CXC...
ORGANISM(S): Mus musculus 
2018-06-30 | E-MTAB-6156 | biostudies-arrayexpress
GenomicsBlocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells
Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells
PRJNA524164 | ENA
TranscriptomicsDifferential RISC association of endogenous human microRNAs predicts their inhibitory potential
It has previously been assumed that the generally high stability of microRNAs (miRNAs) reflects their tight association with Argonaute (Ago) proteins, essential components of the RNA-induced silencing complex (RISC). However, recent data have suggested that the majority of mature miRNAs are not, in ...
ORGANISM(S): Homo sapiens 
2014-05-30 | E-GEOD-58127 | biostudies-arrayexpress
GenomicsThe inhibitory receptor Siglec-G controls the severity of chronic lymphocytic leukemia
The inhibitory receptor Siglec-G controls the severity of chronic lymphocytic leukemia
PRJNA946633 | ENA
Sort   by:  
 Page size