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TranscriptomicsExpression profile of splenocytes with glucose-6-phosphate isomerase (GPI) induced arthritis
To explore TNF-related genes in GPI-induced arthritis, we performed GeneChip analysis using arthritic splenocytes and control-immunized splenocytes. Among the arrayed TNFalpha-related genes, TIARP mRNA was highly expressed in arthritic splenocytes, with levels exceeding more than 20-times the contro...
ORGANISM(S): Mus musculus 
2010-03-03 | E-GEOD-17272 | biostudies-arrayexpress
TranscriptomicsGene expression profile of TIARP-deficient macrophages or neutrophils, compared with WT macrophages or neutrophils
[Background] TNFa-induced adipose-related protein (TIARP) is a six-transmembrane protein that is expressed on macrophages, neutrophils and synoviocytes. We have recently reported that TIARP deficient mice (TIARP-/-) spontaneously developed arthritis, and had the high susceptibility to collagen-induc...
ORGANISM(S): Mus musculus 
2015-09-23 | E-GEOD-73306 | biostudies-arrayexpress
ProteomicsSmoothened Transduces Hedgehog Signals via Activity-Dependent Sequestration of PKA Catalytic Subunits
The Hedgehog (Hh) pathway is essential for organ development, homeostasis, and regeneration. Dysfunction of this cascade drives several cancers. To control expression of pathway target genes, the G protein-coupled receptor (GPCR) Smoothened (SMO) activates glioma-associated (GLI) transcription facto...
ORGANISM(S): Homo Sapiens 
2021-04-25 | PXD023893 | panorama
UnknownKey phosphorylation sites in GPCRs orchestrate the contribution of ?-Arrestin 1 in ERK1/2 activation
Not available
S-SCDT-EMBOR-2019-49886V1P | biostudies-other
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