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TranscriptomicsTranscriptional response of confluent human umbilical vein endothelial cells to stimulation with the related cytokines interleukin-1b or interleukin-33.
The similar response of endothelial cells to exogenous IL-33 or IL-1M-NM-2 prompted us to compare the genome-wide transcription profile of confluent human umbilical vein endothelial cell (HUVEC) cultures after 4 hours exposure to IL-33 or IL-1M-NM-2. Analysis of these data revealed a striking simila...
ORGANISM(S): Homo sapiens 
2013-03-05 | E-GEOD-37624 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of neonatal rat ventricular cardiac myocytes treated with interleukin 33 for 0.5, 1 or 2 hours
Study of the effect of interleukin 33 (IL33) on transcript expression in neonatal rat ventricular cardiac myocytes at 0.5, 1 or 2 h
ORGANISM(S): Rattus norvegicus 
2010-04-01 | E-MEXP-1912 | biostudies-arrayexpress
TranscriptomicsIL-33 activates tumor stroma to promote intestinal polyposis
Tumor epithelial cells develop within a microenvironment consisting of extracellular matrix, growth factors, and cytokines produced by non-epithelial stromal cells. In response to paracrine signals from tumor epithelia, stromal cells modify the microenvironment to promote tumor growth and metastasis...
ORGANISM(S): Homo sapiens 
2015-04-29 | E-GEOD-62518 | biostudies-arrayexpress
ProteomicsA proteomic landscape of the spatiotemporal influence of Interleukin-33 (IL-33) in monocytes
Interleukin-33 (IL-33), a member of the IL-1 superfamily cytokines, is an endogenous danger signal and a nuclear-associated cytokine. It is one of the essential mediators of both innate and adaptive immune responses. Aberrant IL-33 signaling has been demonstrated to play a defensive role against var...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD028673 | Pride
Innate immunity Inflammation Cytokines Mass spectrometry Signaling Monocytes 
GenomicsInterleukin-33 (IL-33) promotes DNA damage-resistance in lung cancer
Interleukin-33 (IL-33) promotes DNA damage-resistance in lung cancer
PRJNA1189817 | ENA
GenomicsKnockdown of interleukin-33 in human fibroblasts
Knockdown of interleukin-33 in human fibroblasts
PRJNA630484 | ENA
TranscriptomicsThe alarmin interleukin-33 drives protective antiviral CD8+ T cell responses
Pathogen-associated molecular patterns decisively influence antiviral immune responses, whereas the contribution of endogenous signals of tissue damage, also known as “damage-associated molecular patterns” or “alarmins”, remains ill-defined. We show that interleukin-33 (IL-33), an alarmin released f...
ORGANISM(S): Mus musculus 
2012-02-27 | E-GEOD-34392 | biostudies-arrayexpress
ProteomicsDataset of spatiotemporal influences of interleukin IL-1 family cytokine: Interleukin-33 on cellular signal transduction pathways
Interleukin-33 (IL-33) is a member of the IL-1 family of cytokines that play a central role in the regulation of immune responses. IL-33 signaling, from the early signaling events triggered by the ligand-activated receptor to result in activation of early and late signaling events, such as proteome...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD024385 | Pride
Mass spectrometry Cytokines Il-33 Monocytes 
TranscriptomicsIL-33 induces a hypo-responsive human mast cell phenotype
Interleukin-33 (IL-33) is elevated in afflicted tissues of patients with mast cell-dependent chronic allergic diseases. Based on its acute effects on mouse mast cells (MCs), IL-33 is thought to play a role in the pathogenesis of allergic disease through MC activation. However, the manifestations of ...
ORGANISM(S): Mus musculus 
2013-02-06 | E-GEOD-39382 | biostudies-arrayexpress
GenomicsGlioma cells response Interleukin-33 (IL-33) [microarray]
Glioma cells response Interleukin-33 (IL-33) [microarray]
PRJNA642838 | ENA
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