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GenomicsOpposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression
Interleukin 9 (IL-9) is a γc-family cytokine that is highly produced by T-helper 9 (Th9) cells and regulates a range of immune responses, including allergic inflammation. Here we show that IL-2–JAK3–STAT5 signaling is required for Th9 differentiation, with critical STAT5 binding sites in the Il9 (th...
ORGANISM(S): Mus musculus 
2014-02-20 | E-GEOD-41317 | biostudies-arrayexpress
GenomicsIdentification of a novel interleukin-9 receptor complex in non-hematopoietic cells
Identification of a novel interleukin-9 receptor complex in non-hematopoietic cells
PRJNA1251590 | ENA
TranscriptomicsInduction of Interleukin-9-producing Mucosal Mast cells Promotes Susceptibility to IgE-mediated Experimental Food Allergy
Experimental IgE-mediated food allergy depends on intestinal anaphylaxis driven by interleukin (IL)-9. However, the primary cellular source of IL-9 and the mechanisms underlying the susceptibility to food-induced intestinal anaphylaxis remain unclear. Herein, we have reported the identification of m...
ORGANISM(S): Mus musculus 
2015-09-11 | E-GEOD-72921 | biostudies-arrayexpress
GenomicsAn Interleukin 9-ZBTB18 axis promotes germinal center development of memory B cells
An Interleukin 9-ZBTB18 axis promotes germinal center development of memory B cells
PRJNA1215750 | ENA
GenomicsAn Interleukin 9-ZBTB18 axis promotes germinal center development of memory B cells [ATAC-seq]
An Interleukin 9-ZBTB18 axis promotes germinal center development of memory B cells [ATAC-seq]
PRJNA1216282 | ENA
TranscriptomicsTranscriptional profiling of human IL-9R+ T helper cells in presence of recombinant IL-9 against untreated control
To study the effect of paracrine interleukin-9 (IL-9) on T helper cells, we incubated IL-9R+ T helper cells isolated from blood (5 samples) and skin (3 samples) with or without IL-9 for 12h and the transcriptome was analyzed by bulk RNA-seq.
ORGANISM(S): Homo sapiens 
2022-10-31 | E-MTAB-12204 | biostudies-arrayexpress
TranscriptomicsGene expression profiling from TS1 and TS2 cells in biological duplicates (A and B)
TS1 and TS2 are T-lymphocyte derived cell lines that striclty depend on the presence of interleukin-9 for growth and survival. The goal of the study was to compare gene expression profiles between those 2 cell lines. TS1 and TS2 cell lines were maintained in vitro under the same conditions. RNA was ...
ORGANISM(S): Mus musculus 
2015-07-01 | E-GEOD-70395 | biostudies-arrayexpress
TranscriptomicsAn Interleukin 9-ZBTB18 axis promotes germinal center development of memory B cells
Memory B cell (MBC) development from germinal centers (GCs) entail profound changes in cell cycling, localization and survival. Here we examined the mechanisms that induce the memory program, focusing on interleukin (IL)-9, given its importance for normal recall antibody responses. Using adoptive tr...
ORGANISM(S): Mus musculus 
2025-03-01 | GSE288037 | GEO
UnknownFirst Characterization of Chicken Interleukin-9.
Not available
S-EPMC9252340 | biostudies-literature
ProteomicsDifferentially expressed proteins in Human Primary Keratinocytes upon IL-9 stimulation
HPKs from 3-5 healthy individual donors were pre-stimulated with TGFb (10ng/ml) plus IL-4 (20ng/ml) to upregulated the IL-9R (Das et al., 2019). Next day, HPKs were stimulated with IL-9 (50ng/ml) or in combination with IFNg (10ng/ml) for 24 hours at 37 degree C with 5% CO2. Sample preparation for L...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-28 | MSV000086776 | MassIVE
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