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Impaired mitochondrial proteostasis underlies a broad spectrum of diseases, yet effective therapies remain limited. Here, we show that deficiency of HTRA2, a mitochondrial intermembrane space protease, can be rescued by hypoxia therapy. Using an Htra2 mutant mouse model that displays severe neurodeg...
ORGANISM(S): Mus musculus 
2026-05-29 | GSE327486 | GEO
Data contains LC-MS data of proximity-based biotin labeling assay (BioID) to generate the protein interaction network of mitochondrial intermembrane space proteases fused with BirAFlag (C-terminal tag) and expressed in T-REx HEK293 cells.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-11-14 | MSV000083140 | MassIVE
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