Invasive breast cancer

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Unknown (6500)
Transcriptomics (968)
Genomics (845)
Proteomics (108)
Genomic (22)
Methylation profiling (21)
Other (21)
Clinical (17)
Metabolomics (10)
Multiomics (1)

Organisms

Homo sapiens (1075)
Mus musculus (162)
Aerococcus urinae NBRC 15544 = CCUG 36881 (75)
Allexis (75)
Canis lupus familiaris (75)
Carya cathayensis (75)
Clostridioides difficile 630 (75)
Cyanophora paradoxa (75)
Ensifer adhaerens (75)
Enterococcus faecalis (75)
Globicatella sanguinis (75)
Histomonas meleagridis (75)
Human immunodeficiency virus 1 (75)
Listeria monocytogenes (75)
Marchantia polymorpha (75)
Methylohalobius crimeensis 10Ki (75)
Mus musculus (75)
Mycobacterium tuberculosis (75)
Ophrys garganica (75)
Rattus norvegicus (11)
synthetic construct (4)
Canis lupus familiaris (2)
Mus musculus x Mus spretus (1)
Macaca mulatta (1)
Streptococcus pyogenes (1)
Halobacterium salinarum (1)
Oryctolagus cuniculus (1)
Bos taurus (1)
Escherichia coli str. K-12 substr. MG1655 (1)
Drosophila melanogaster (1)

Organisms

Homo sapiens (475)
Mus musculus (69)
Canis lupus familiaris (2)
Rattus norvegicus (1)

Repository

biostudies-arrayexpress (685)
ENA (609)
geo (442)
EGA (116)
pride (75)
dbGaP (22)
MassIVE (14)
iProX (9)
MetaboLights (9)
ExpressionAtlas (8)
jPOST (2)
PanoramaPublic (2)
GNPS (1)
GPMDB (1)

Tissue

Breast (13)
Liver (5)
Lung (4)
Uterine cervix (3)
Esophagus (3)
Large intestine (3)
Stomach (3)
Pancreas (3)
Ovary (3)
Uterus (3)
Urinary bladder (3)
Skin (3)
Prostate gland (3)
Thyroid gland (3)
Brain (3)
Kidney (3)
Mouth mucosa (2)
Skeletal muscle tissue (2)
Blood (2)
Bone (2)
Musculature (1)
Hematopoietic system (1)
Peripheral nervous system (1)
Vulva (1)
Mucosa (1)
Connective tissue (1)
Bile duct (1)
Placenta (1)
Gall bladder (1)
Adrenal gland (1)

Disease

Invasive ductal carcinoma (8)
Normal (6)
Breast adenocarcinoma (5)
Cholangiocarcinoma (5)
Renal cell carcinoma (4)
Pancreatic adenocarcinoma (4)
Follicular thyroid carcinoma (4)
Gastric adenocarcinoma (4)
Hepatocellular carcinoma (4)
Bladder transitional cell carcinoma (4)
Invasive lobular carcinoma (4)
Head and neck squamous cell carcinoma (4)
Squamous cell lung carcinoma (4)
Cervical squamous cell carcinoma (4)
Ovarian adenocarcinoma (4)
Melanoma (4)
Esophageal adenocarcinoma (4)
Lung adenocarcinoma (4)
Lymphoma (4)
Breast carcinoma (4)
Cervical adenocarcinoma (3)
Glioblastoma multiforme (3)
Colorectal adenocarcinoma (3)
Prostate adenocarcinoma (3)
Sarcoma (3)
Chronic lymphocytic leukemia (3)
Endometrial adenocarcinoma (3)
Glioma (3)
Anaplastic astrocytoma (2)
Chondrosarcoma (2)

Technology Type

Mass Spectrometry (75)
Shotgun proteomics (44)
Bottom-up proteomics (12)
Affinity purification coupled with mass spectrometry proteomics (9)
SWATH MS (8)
Mass spectrometry (4)
Data-independent acquisition (4)
NMR spectroscopy (3)
Data-dependent acquisition (3)
Gel-based experiment (3)
Illumina Genome Analyzer II, Illumina HiSeq 2000 (2)
Illumina HiSeq 2000 (2)
MSE (2)
ILLUMINA, NextSeq 500 (1)
Affymetrix OncoScan FFPE Express (1)
Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500 (1)
Affymetrix SNP 6.0 (1)
CYTOSCANHD, ILLUMINA, HUMANOMNI1QUAD, HUMANOMNIEXPRESS, Affymetrix HG_U133_+2, Illumina HiSeq 2000 (1)
Illumina HiSeq 2500 (1)
Illumina MiSeq (1)
Illumina HiSeq 2000, ILLUMINA (1)
NMR spectroscopy assay (1)
Mass spectrometry assay (1)
DiaPASEF (1)
HDMSE (1)

Instrument Platform

Illumina NovaSeq 6000 (21)
NextSeq 500 (18)
Illumina HiSeq 4000 (13)
Illumina HiSeq 2000 (11)
Q Exactive (8)
Illumina HiSeq 2500 (5)
Illumina HiSeq 1500 (3)
Exactive (3)
Illumina Genome Analyzer IIx (2)
Axon- GenePix4000B (2)
GenePix 4000B [Axon Instruments] (2)
Illumina MiSeq (2)
NEXTflex Small-RNA Seq kit v3 (Perkin Elmer) & NEXTflex Rapid XP DNA-seq kit v2 (Perkin Elmer) (1)
Direct-zol RNA microprep kit (Zymo Research), LabChip RNA pico sensitivity assay, Perkin Elmer & Nucleospin RNA kit (Macherey Nagel) (1)
PALM type 4 microscope (Zeiss) (1)
Agilent 2100 bioanalyzer (1)
NanoDrop ND-1000 (1)
MoFlo Legacy cell sorter (Beckman Coulter) (1)
PC (1)
AgilentM-^Rs Microarray Hybridization Oven (1)
Affymetrix Genechip Command Console software (1)
Trizol Reagent (1)
454 GS 20 (1)
Agilent Technologies Scanner G2505C (1)
ScanArray 4000 [PerkinElmer] (1)
The Agilent scanner G2565BA (1)
NanoDrop ND-1000 Spectrophotometer (NanoDrop Technologies) (1)
Illumina Genome Analyzer II (1)
NextSeq 2000 (1)
Instrument (1)

Publication Date

2014 (111)
2013 (102)
2011 (100)
2012 (99)
2010 (96)
2015 (81)
2016 (78)
2022 (74)
2025 (57)
2026 (53)
2008 (50)
2020 (44)
2009 (44)
2023 (43)
2021 (40)
2017 (37)
2024 (36)
2019 (33)
2018 (29)
2007 (16)
2006 (15)
2005 (4)
2002 (1)

CHEBI ID

CHEBI:78320 (4)
CHEBI:16919 (4)
CHEBI:27897 (4)
CHEBI:48430 (3)
CHEBI:27570 (3)
CHEBI:17154 (3)
CHEBI:30751 (3)
CHEBI:15428 (3)
CHEBI:16811 (3)
CHEBI:16870 (3)
CHEBI:15366 (3)
CHEBI:25017 (3)
CHEBI:17053 (3)
CHEBI:37024 (3)
CHEBI:7916 (3)
CHEBI:18132 (3)
CHEBI:18012 (3)
CHEBI:32816 (3)
CHEBI:15741 (3)
CHEBI:17268 (3)
CHEBI:15354 (3)
CHEBI:4167 (2)
CHEBI:35932 (2)
CHEBI:16857 (2)
CHEBI:17754 (2)
CHEBI:15347 (2)
CHEBI:37084 (2)
CHEBI:16797 (2)
CHEBI:15846 (2)
CHEBI:17822 (2)

Metabolite Name

Alanine (4)
Glycine (4)
Glucose (4)
2-Oxoisocaproate (3)
O-Phosphocholine (3)
Formate (3)
Histidine (3)
Sn-Glycero-3-phosphocholine (3)
Leucine (3)
Glycerol (3)
Valine (3)
Methionine (3)
Lactate (3)
Tyrosine (3)
Serine (3)
Threonine (3)
Phenylalanine (3)
Isoleucine (3)
Fumarate (3)
Myo-Inositol (3)
Creatine (3)
3-Methyl-2-oxovalerate (2)
3-Hydroxyisovalerate (2)
Acetate (2)
Beta-Alanine (2)
1-Methylnicotinamide (2)
Pantothenate (2)
Acetone (2)
Arabinose (2)
Putrescine (2)

First Public Date

2014 (163)
2024 (58)
2022 (51)
2026 (40)
2025 (40)
2023 (38)
2021 (38)
2015 (37)
2020 (34)
2019 (28)
2017 (27)
2016 (20)
2018 (19)
2013 (16)

Study status

Recruiting (6)
Completed (6)
Ongoing (2)
Withdrawn (1)
Active, not recruiting (1)
Not provided (1)

Study type

Transcription profiling by array (418)
Comparative genomic hybridization by array (51)
RNA-seq of coding RNA (50)
ChIP-seq (25)
Methylation profiling by array (25)
Other (13)
RNA-seq of coding RNA from single cells (12)
DNA-seq (11)
ChIP-chip by array (9)
MicroRNA profiling by array (8)
RNA-seq of non coding RNA (8)
Unknown experiment type (7)
ChIP-chip by tiling array (6)
Genotyping by array (6)
Methylation profiling by high throughput sequencing (6)
Human - High-throughput sequencing (4)
Transcription profiling by RT-PCR (4)
Proteomic profiling by array (4)
RNA-seq of total RNA (3)
Animal - High-throughput sequencing (2)
Cell line - High-throughput sequencing (2)
Single nucleus RNA sequencing (2)
RAN-seq of total RNA from single cells (1)
Transcription profiling by SAGE (1)
RNA-seq of non coding RNA from single cells (1)
One-color microarray (1)
Human - Single-cell sequencing (1)
High-throughput sequencing (1)
RNAi profiling by array (1)
CUT&RUN (1)

Release Date

2022 (677)
2021 (645)
2023 (624)
2025 (588)
2024 (567)
2020 (532)
2016 (496)
2017 (406)
2019 (401)
2018 (385)
2015 (324)
2014 (315)
2013 (240)
2012 (229)
2011 (191)
2010 (163)
2009 (106)
2026 (97)
2008 (96)
2007 (39)
2006 (27)
2005 (12)
2004 (6)
2002 (5)
2001 (5)
2003 (4)
1999 (3)
2000 (1)

Lab affiliation

Centro de Investigación Príncipe Felipe, Av. Eduardo Primo Yúfera 3, 46012 Valencia, Spain (2)
Department of Biochemistry and Molecular Biology & The Center for Systems Biology University of Iceland Sturlugata 8, 101 Reykjavik Iceland. (2)
Functional Proteomics, ICR (2)
1. Division of Experimental Medicine, McGill University, Montreal, QC 2. Segal Cancer Proteomics Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC 3. Department of Pathology, Segal Cancer Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, QC 4. Segal Cancer Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC 5. Department of Oncology, McGill University, Montreal, QC (1)
Aberystwyth University (1)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
Assistant Professor, Departments of Oncology & Pathology, McGill University Principal Investigator, Cancer Research Program, MUHC-RI 1001 Decarie Blvd, EM2.2218 514.934.1934 ext 76307 Montréal, Canada (1)
BioOrganic Mass Spectrometry laboratory (LSMBO) Institut Plurisciplinaire Hubert Curien University of Strasbourg. France (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, 3584 CH Utrecht, Netherlands. (1)
Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), DK-2200 Copenhagen, Denmark (1)
CNIO (1)
CRUK Beatson Institute (1)
Cancer Research UK, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE (1)
Cedars-Sinai Medical Institute, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA (1)
Center for Applied Proteomics & Molecular Medicine, George Mason University, Manassas, VA (1)
Central Laboratory, Wuxi Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University (1)
Centre de Recherche en Cancérologie de Marseille, CRCM Marseille Proteomique Inserm UMR1068, CNRS UMR7258, Aix Marseille Université U105,z Institut Paoli Calmettes 27 Boulevard Leï Roure CS30059 13273 Marseille Cedex 09 France (1)
Centre for Gene Regulation and Expression University of Dundee (1)
Clarkson University (1)
Core Facility Proteomics, Department of Clinical Chemistry, University Medical Center Göttingen, Germany (1)
Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill,NC 27599,USA (1)
Department of Biomedical Engineering, Tufts University, United States (1)
Department of Cellular and Molecular Pharmacology Quantitative Biosciences Institute University of California San Francisco San Francisco, CA 94158, USA (1)
Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA (1)
Department of Chemistry and Biomolecular Sciences, University of Ottawa, Canada (1)
Department of Chemistry and Biomolecular Sciences, University of Ottawa, Canada (lab head) (1)
Department of Human Molecular Genetics and Biochemistry Sackler Faculty of Medicine, Tel Aviv University Israel (1)
Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel (1)
Department of Medical Oncology, Harbin Medical University Cancer Hospital, Heilongjiang Cancer Institute, Harbin 150081, Heilongjiang Province, People闁炽儲鐛� Republic of China. (1)
Department of Molecular Biomedicine, CINVESTAV-IPN (1)

Location

United States (11)
Canada (3)
China (2)
Guam (1)
Spain (1)
United Kingdom (1)
Austria (1)

Keyword

Vaccines (2)
Imipramine (1)
68Ga-NODAGA-RGD (1)
Letrozole (1)
Ziv-aflibercept (1)
All types metastatic cancer where at least one tumor lesion is accessable for percutaneous cryoablation (1)
Adjuvants, Vaccine (1)
High Risk (1)
Molecular Profiling (1)
Hematological (1)
GI cancer (1)
Interleukin-12 (1)
Albumin-Bound Paclitaxel (1)
Next Generation Sequencing (1)
Blood (1)
Liquid Biopsy (1)
Stage I breast cancer (1)
Stage I non-small cell lung cancer (1)
Stage II non-small cell lung cancer (1)
Pulmonary carcinoid tumor (1)
Stage II breast cancer (1)
Stage I prostate cancer (1)
Stage IIB prostate cancer (1)
Stage IIA prostate cancer (1)
Carboplatin (1)
NSABP (1)
Palbociclib (1)
Metronidazole (1)
Stage I rectal cancer (1)
Stage IIIA non-small cell lung cancer (1)

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Metabolomic alterations in invasive ductal carcinoma of breast: A comprehensive metabolomic study using tissue and serum samples

Invasive ductal carcinoma (IDC) is the most common type of breast cancer and the leading cause of breast cancer related mortality. In the present study, metabolomic profiles of 72 tissue samples and 146 serum samples were analysed using targeted liquid chromatography multiple reaction monitoring mas...

2018-10-16 | MTBLS552 | MetaboLights

Organotypic microfluidic breast cancer model reveals starvation-induced spatial-temporal metabolic adaptations

BACKGROUND: Ductal carcinoma in situ (DCIS) is the earliest stage of breast cancer. During DCIS, tumor cells remain inside the mammary duct, growing under a microenvironment characterized by hypoxia, nutrient starvation, and waste product accumulation; this harsh microenvironment promotes genomic in...

2019-02-08 | MTBLS669 | MetaboLights

Multi-omics characterization of acquired Olaparib resistance in BRCA1 and BRCA2 mutant breast cancer cell lines

Poly (ADP-ribose) polymerase inhibitors (PARPi) are widely used as targeted therapies against breast cancers with BRCA mutations. However, the development of resistance to PARPi poses a significant challenge for long-term efficacy of these therapies, warranting further understanding of mechanisms of...

2026-05-11 | MTBLS12109 | MetaboLights

The Poly (ADP-Ribose) Polymerase inhibitor Veliparib and Radiation Cause Significant Cell Line Dependent Metabolic Changes in Breast Cancer Cells

Breast tumors are characterized into different subtypes based on their surface marker expression, which affects their prognosis and treatment. For example, triple negative breast cancer cells (ER-/PR-/Her2-) show reduced susceptibility towards radiotherapy and chemotherapeutic agents. Poly (ADP-ribo...

2016-11-07 | MTBLS337 | MetaboLights

Metabolic phenotyping of ex-vivo breast samples by DESI mass spectrometry imaging

This study involves the analysis of surgically resected samples from patients undergoing breast surgery. The samples published here have been used as part of the publication by [1], and all experimental details can be found within. Desorption electrospray ionisation mass spectrometry imaging (DESI M...

2016-04-28 | MTBLS273 | MetaboLights

1H NMR-Based Plasma Metabolomics and Machine Learning Reveal Distinct Metabolic Signatures of Breast Cancer in Nigerian Women

Metabolic dysregulation is a hallmark of cancer and provides insights into biomarker discovery. Untargeted 1H NMR metabolomics offers a non-invasive means to identify biomarkers in breast cancer (BC) patients; however, metabolic signatures specific to Nigerian women remain poorly understood. This...

2026-02-23 | MTBLS13829 | MetaboLights

Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer

This SuperSeries is composed of the following subset Series: GSE41194: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer (Group 1) GSE41196: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive...

ORGANISM(S): Homo sapiens

2012-09-29 | E-GEOD-41228 | biostudies-arrayexpress

Transcription profiling by array of human breast epithelium and stroma in normal reduction mammoplasty and invasive breast cancer patients

The molecular basis of breast cancer invasion and metastasis is not well understood. Our objective was to analyze transcriptome differences between stromal and epithelial cells in normal breast tissue and invasive breast cancer to define the role stroma plays in invasion. Total RNA was isolated fr...

ORGANISM(S): Homo sapiens

2009-03-07 | E-GEOD-10797 | biostudies-arrayexpress

Validation cohort for genomic predictor of response and survival following neoadjuvant taxane-anthracycline chemotherapy in breast cancer

PURPOSE: To develop a predictive test for response and survival following neoadjuvant taxane-anthracycline chemotherapy for HER2-negative invasive breast cancer. METHODS: We developed a microarray-based gene expression test from pre-treatment tumor biopsies (310 patients) to predict favorable outcom...

ORGANISM(S): Homo sapiens

2011-05-11 | E-GEOD-25065 | biostudies-arrayexpress

Discovery cohort for genomic predictor of response and survival following neoadjuvant taxane-anthracycline chemotherapy in breast cancer

ORGANISM(S): Homo sapiens

2011-05-11 | E-GEOD-25055 | biostudies-arrayexpress

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