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MetabolomicsMetabolomic alterations in invasive ductal carcinoma of breast: A comprehensive metabolomic study using tissue and serum samples
Invasive ductal carcinoma (IDC) is the most common type of breast cancer and the leading cause of breast cancer related mortality. In the present study, metabolomic profiles of 72 tissue samples and 146 serum samples were analysed using targeted liquid chromatography multiple reaction monitoring mas...
2018-10-16 | MTBLS552 | MetaboLights
TranscriptomicsDifferentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer
This SuperSeries is composed of the following subset Series: GSE41194: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer (Group 1) GSE41196: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive...
ORGANISM(S): Homo sapiens 
2012-09-29 | E-GEOD-41228 | biostudies-arrayexpress
TranscriptomicsGene Expression and Comparative Genomic Hybridization of Ductal Carcinoma In Situ of the Breast
Background The dramatic increase in incidence of ductal carcinoma in situ (DCIS) associated with mammographic screening for breast cancer has given emphasis to the challenges of managing this important clinical entity. Unlike invasive breast cancer, there is no established histopathologic grading sy...
ORGANISM(S): Homo sapiens 
2008-11-24 | E-GEOD-7882 | biostudies-arrayexpress
TranscriptomicsIdentification of copy number alterations associated with the progression of DCIS to Invasive Ductal Carcinoma
Ductal carcinoma in situ (DCIS) is a non-obligate precursor to invasive ductal carcinoma (IDC). Annotation of the genetic differences between the two lesions may assist in the identification of genes that promote the invasive phenotype. Matched IDC and DCIS showed highly similar copy number profile...
ORGANISM(S): Homo sapiens 
2012-09-04 | E-GEOD-31892 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human ductal carcinoma in situ (DCIS) and invasive component (IDC) from 9 breast cancers to identify novel molecular markers characterizing the transition from DCIS to IDC.
This is a matched-pair analysis of ductal carcinoma in situ (DCIS) and invasive component (IDC) of nine breast ductal carcinoma to identify novel molecular markers characterizing the transition from DCIS to IDC for a better understanding of its molecular biology.
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-3893 | biostudies-arrayexpress
TranscriptomicsExpression profiling of human DCIS and invasive ductal breast carcinoma
Human healthy tissue samples, DCIS and invasive mammary tumors were analyzed in order to identify marker genes which show enhanced expresssion in DCIS and invasive ductal carcinomas. Using this approach, we were able to identify a set of genes which might allow a better detection of DCIS and invasiv...
ORGANISM(S): Homo sapiens 
2011-04-11 | E-GEOD-21422 | biostudies-arrayexpress
TranscriptomicsDuctal Carcinoma Progression
To obtain insight into the molecular basis of ductal carcinoma in situ (DCIS) and its progression by infiltrating surrounding tissue, we have performed cellular-based gene expression analysis of pure DCIS and DCIS with co-existing invasive ductal carcinoma (IDC) and compared the histological and mol...
ORGANISM(S): Homo sapiens 
2008-04-04 | E-GEOD-11042 | biostudies-arrayexpress
TranscriptomicsExpression profiling of murine DCIS and invasive ductal breast carcinoma
Murine healthy tissue samples, DCIS and invasive mammary tumors were analyzed in order to identify marker genes which show enhanced expresssion in DCIS and invasive ductal carcinomas. Using this approach, we were able to identify a set of genes which might allow a better detection of DCIS and invasi...
ORGANISM(S): Mus musculus 
2011-04-11 | E-GEOD-21444 | biostudies-arrayexpress
TranscriptomicsDifferentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer (Group 3)
We used gene expression profiling of human DCIS and IBC to discover uniquely expressed genes that may also regulate progression. RNA from human samples were extracted, purified, amplified, and evaluated for gene expression using Affymetrix U95Av2 gene expression arrays.
ORGANISM(S): Homo sapiens 
2012-09-29 | E-GEOD-41197 | biostudies-arrayexpress
TranscriptomicsIntegration of transcript expression, copy number and LOH analysis of infiltrating ductal carcinoma of the breast
This SuperSeries is composed of the following subset Series: GSE22544: Integration of transcript expression, copy number and LOH analysis of infiltrating ductal carcinoma of the breast: expression analysis GSE22839: Integration of transcript expression, copy number and LOH analysis of infiltrating d...
ORGANISM(S): Homo sapiens 
2010-07-16 | E-GEOD-22840 | biostudies-arrayexpress
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