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ProteomicsIdentification of inositol 1,4,5-trisphosphate-binding proteins by heparin-agarose affinity purification and LTQ ORBITRAP MS in Oryza sativa
Inositol 1,4,5-trisphosohate (IP3) and its receptors play a pivotal role in calcium signal transduction in mammals. Some fractions of tonoplast and endoplasmic reticulum membranes have high affinity binding activity for IP3, and IP3 can induce Ca2+ release in several plants. However, no homologues o...
ORGANISM(S): Oryza sativa (Rice) 
2014-09-25 | PXD000763 | Pride
Oryza sativa Ip3 Ip3 binding protein Ltq orbitrap ms Heparin-agarose 
UnknownControl of Ca2+ influx in human neutrophils by inositol 1,4,5-trisphosphate (IP3) binding: differential effects of micro-injected IP3 receptor antagonists.
Not available
S-EPMC1221721 | biostudies-literature
UnknownDissecting the neuroprotective interaction between the BH4 domain of BCL-w and the IP3 receptor.
Not available
S-EPMC11490406 | biostudies-literature
TranscriptomicsRNAseq analysis of murine ITPKB deficient versus wild type LT-HSC
Tight regulation of hematopoietic stem cell (HSC) homeostasis is essential for life-long hematopoiesis, for preventing blood cancers and for averting bone marrow failure. The underlying mechanisms are incompletely understood. Here, we identify production of inositol-tetrakisphosphate (IP4) by inosit...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-56613 | biostudies-arrayexpress
Unknownp53 upregulates PLCε-IP3-Ca2+ pathway and inhibits autophagy through its target gene Rap2B.
Not available
S-EPMC5630284 | biostudies-literature
UnknownCombining IP3 affinity chromatography and bioinformatics reveals a novel protein-IP3 binding site on Plasmodium falciparum MDR1 transporter.
Not available
S-EPMC9792294 | biostudies-literature
UnknownProtein phosphatase-1 is a novel regulator of the interaction between IRBIT and the inositol 1,4,5-trisphosphate receptor.
Not available
S-EPMC2049018 | biostudies-literature
MetabolomicsInositol triphosphate-triggered calcium release blocks lipid exchange at endoplasmic reticulum-Golgi contact sites
Vesicular traffic and membrane contact sites between organelles enable the exchange of proteins, lipids, and metabolites. Recruitment of membrane tethers to contact sites between the endoplasmic reticulum (ER) and the plasma membrane is often triggered by calcium. In contrast, we reveal here a funct...
2021-05-06 | MTBLS2444 | MetaboLights
UnknownFK506 regulates Ca<sup>2+</sup> release evoked by inositol 1,4,5-trisphosphate independently of FK-binding protein in endothelial cells.
Not available
S-EPMC7042112 | biostudies-literature
ModelsMazet2020 - model of the PI cycle
PI cycle Core Model Global Quantities = free + bound PL for PI, PIP2, PI4P, PIP3, PI34P2, DAG, PA. For PI initial quantity added in GQ is in organelle membranes NB: all labeled [xxgl] in plots select L.GPCR for GPCR simulations in Events select R for GqPCR receptor number simulations relevant pl...
2020-06-30 | MODEL2006300001 | BioModels
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