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TranscriptomicsTranscription profiling of mouse immature pDC and pDC activated with CpG 1826 and influenza virus PR8
CpG 1826 binds to Toll-like receptor (TLR)9, whereas influenza virus PR8 activates pDC via TLR7. Differential stimulation of pDCs is expected to result in unique activation mechanism(s) leading to a different phenotypically and functionally matured pDC; We used microarrays to detail the global progr...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7831 | biostudies-arrayexpress
TranscriptomicsGene expression data from murine mDC and pDC
mDC and pDC exhibit distinct TLR expression pattern and differ in their responses to various TLR ligands. The goal of this study was to identify genes, that were differentally expressed between mDC and pDC as a means to determine how TLR signaling pathways operate. Suprisingly, expression of TLR-ass...
ORGANISM(S): Mus musculus 
2014-01-01 | E-GEOD-50436 | biostudies-arrayexpress
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