Sort   by:  
 Page size 
TranscriptomicsTranscriptome profiling of irg1 mutant leaf of Medicago truncatula
To gain a molecular understanding of the loss-of-function mutation of a transcription factor involved in leaf morphogenesis impacts symmetric cuticular wax loading in M. truncatula, we compared the transcript profiles of wild-type R108 and three independent irg1/palm1 homozygous null mutant lines (i...
ORGANISM(S): Medicago truncatula 
2012-03-01 | E-MEXP-3190 | biostudies-arrayexpress
GenomicsLactiplantibacillus plantarum strain:IRG1
Lactobacillus plantarum IRG1 Genome sequencing and assembly
PRJNA428424 | ENA
GenomicsTargeting IRG1 in tumor-associated macrophages for cancer therapy
Targeting IRG1 in tumor-associated macrophages for cancer therapy
PRJNA867712 | ENA
TranscriptomicsLPS stimulation of human PBMC-derived macrophages
Immunoresponsive gene 1 (IRG1) is one of the highest induced genes in macrophages under pro-inflammatory conditions and its function has been recently described: it codes for immune-responsive gene 1 protein/cis-aconitic acid decarboxylase (IRG1/CAD), an enzyme catalyzing the production of itaconic ...
ORGANISM(S): Homo sapiens 
2016-02-25 | E-GEOD-76561 | biostudies-arrayexpress
TranscriptomicsLPS stimulation of Mouse (RAW 264.7) macrophages
Immunoresponsive gene 1 (IRG1) is one of the highest induced genes in macrophages under pro-inflammatory conditions and its function has been recently described: it codes for immune-responsive gene 1 protein/cis-aconitic acid decarboxylase (IRG1/CAD), an enzyme catalyzing the production of itaconic ...
ORGANISM(S): Mus musculus 
2016-02-25 | E-GEOD-76562 | biostudies-arrayexpress
GenomicsIRG1/itaconate axis modulates lung tumor microenvironment via pentose phosphate pathway [sav25]
IRG1/itaconate axis modulates lung tumor microenvironment via pentose phosphate pathway [sav25]
PRJNA1077934 | ENA
ProteomicsA new NO-independent immunomodulatory function for iNOS in regulating itaconate production via mitochondrial protein-protein interaction with IRG1
iNOS modulates itaconate metabolism by a novel conformation-dependent protein-protein interaction separate from iNOS-mediated NO generation.
ORGANISM(S): Homo sapiens (Human) 
2026-02-20 | PXD048712 | Pride
Macrophages Tca cycle by cis-aconitate decarboxylase Inos and irg1 
GenomicsIRG1/itaconate axis modulates lung tumor microenvironment via pentose phosphate pathway [sav24]
IRG1/itaconate axis modulates lung tumor microenvironment via pentose phosphate pathway [sav24]
PRJNA1077937 | ENA
GenomicsEffects of Irg1-itaconate or Hemin on gene expression in macrophages [RNA-seq]
Effects of Irg1-itaconate or Hemin on gene expression in macrophages [RNA-seq]
PRJNA915639 | ENA
TranscriptomicsTargeting IRG1 in tumor-associated macrophages for cancer therapy
Immune-responsive gene 1 (IRG1) is a mitochondrial aconitate decarboxylase and can produce the immunomodulatory metabolite itaconic acid (ITA). However, its role in modulating the function of tumor-associated macrophages (TAMs) remains elusive. Here, we show that IRG1 is expressed in TAMs in human t...
ORGANISM(S): Mus musculus 
2023-05-01 | GSE210845 | GEO
Sort   by:  
 Page size