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ProteomicsPolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons
A GGGGCC repeat expansion in C9orf72 is the most common genetic cause of ALS and FTD (C9ALS/FTD). Dipeptide repeat (DPR) proteins, generated by translation of the expanded repeat, are a major pathogenic feature of C9ALS/FTD pathology, but their physiological impact has yet to be fully determined. He...
ORGANISM(S): Mus musculus (Mouse) 
2024-03-04 | PXD047502 | Pride
Tgf-β Collagen vi Frontotemporal dementia Amyotrophic lateral sclerosis Proteomics Col6a1 C9orf72 Extracellular matrix 
UnknownRelationship Between Severity of Ischemia and Coronary Artery Disease for Different Stress Test Modalities in the ISCHEMIA Trial.
Not available
S-EPMC11658795 | biostudies-literature
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