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ProteomicsIntegration of functional imaging, cytometry and unbiased proteomics reveals new features of endothelial-to-mesenchymal transition in ischemic mitral valve regurgitation in human patients
Background: Following myocardial infarction, mitral regurgitation (MR) is a common complication. Previous animal studies demonstrated the association of endothelial-to-mesenchymal transition (EndMT) with mitral valve (MV) remodeling. Nevertheless, little is known about how MV tissue responds to isch...
ORGANISM(S): Homo sapiens (Human) 
2021-08-13 | PXD025096 | Pride
Human Mitral valve (mv) Proteomic Ischemic mitral regurgitation (imr) Echocardiography Endothelial-to-mesenchymal transition (endmt) Histo-cytometry 
GenomicsMitral valve leaflet response to ischemic mitral regurgitation: From gene expression to tissue remodeling
Mitral valve leaflet response to ischemic mitral regurgitation: From gene expression to tissue remodeling
PRJNA587626 | ENA
UnknownOvine Model of Ischemic Mitral Regurgitation.
Not available
S-EPMC6207369 | biostudies-literature
TranscriptomicsMitral valve leaflet response to ischemic mitral regurgitation: From gene expression to tissue remodeling
Rationale: Ischemic mitral regurgitation (IMR) is frequently observed following myocardial infarction (MI) and is associated with higher mortality and poor clinical prognosis if left untreated. Accumulating evidence suggests that mitral valve (MV) leaflets actively remodel post-MI, yet the cellular ...
ORGANISM(S): Ovis aries 
2020-05-06 | GSE139921 | GEO
UnknownProgression of Tricuspid Regurgitation After Surgery for Ischemic Mitral Regurgitation.
Not available
S-EPMC7953587 | biostudies-literature
UnknownSurgical management of moderate ischemic mitral valve regurgitation: Where do we stand?
Not available
S-EPMC4244618 | biostudies-literature
UnknownImpact of Mitral Regurgitation Recurrence on Mitral Valve Repair for Secondary Ischemic Mitral Regurgitation.
Not available
S-EPMC10053850 | biostudies-literature
UnknownTricuspid regurgitation in ischemic mitral regurgitation patients: prevalence, predictors for outcome and long-term follow-up.
Not available
S-EPMC8058984 | biostudies-literature
UnknownLong-Term Outcomes of Mitral Valve Repair Versus Replacement in Patients with Ischemic Mitral Regurgitation: A Retrospective Propensity-Matched Analysis.
Not available
S-EPMC12027820 | biostudies-literature
UnknownA pig model of ischemic mitral regurgitation induced by mitral chordae tendinae rupture and implantation of an ameroid constrictor.
Not available
S-EPMC4257529 | biostudies-literature
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