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TranscriptomicsEpigenetically induced paucity of histone H2A.Z stabilizes fission yeast ectopic centromeres
In most eukaryotes, the centromere is epigenetically defined by nucleosomes that contain the histone H3 variant centromere protein A (CENP-A). Specific targeting of the CENP-A-loading chaperone to the centromere is vital for stable centromere propagation; however, the existence of ectopic centromere...
ORGANISM(S): Schizosaccharomyces pombe 
2013-11-03 | E-GEOD-37094 | biostudies-arrayexpress
TranscriptomicsThe 19S proteasome subunit Rpt3 regulates distribution of CENP-A by associating with centromeric chromatin
CENP-A, a variant of histone H3, is incorporated into centromeric chromatin and plays a role during kinetochore establishment. In fission yeast, the localization of CENP-A is limited to a region spanning 10 to 20 kb of the core domain of the centromere. Here, we report a mutant (rpt3-1) in which thi...
ORGANISM(S): Schizosaccharomyces pombe 
2014-04-07 | E-GEOD-44594 | biostudies-arrayexpress
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