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TranscriptomicsEffect of oocyte-enriched histones Th2a, Th2b, and histone chaperone Npm on mouse iPS cell generation
Expression of key transcription factors Klf4, Oct3/4, Sox2, and c-Myc (KOSM) in embryonic stem cells can reprogram somatic cells into pluripotent cells. We found that two histone variants, TH2A and TH2B, and histone chaperone Npm enhance the KOSM-dependent generation of induced pluripotent cells (iP...
ORGANISM(S): Mus musculus 
2013-12-25 | E-GEOD-53637 | biostudies-arrayexpress
TranscriptomicsATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory (ChIP)
Immunological memory is generally thought to be mediated exclusively by lymphocytes such as memory T and B cells. However, enhanced innate immune responses caused by a previous infection increase protection against reinfection suggesting the presence of innate immunological memory. Here, we describe...
ORGANISM(S): Mus musculus 
2015-08-31 | E-GEOD-71112 | biostudies-arrayexpress
TranscriptomicsATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory (expression)
Immunological memory is generally thought to be mediated exclusively by lymphocytes such as memory T and B cells. However, enhanced innate immune responses caused by a previous infection increase protection against reinfection suggesting the presence of innate immunological memory. Here, we describe...
ORGANISM(S): Mus musculus 
2015-08-31 | E-GEOD-71111 | biostudies-arrayexpress
UnknownQuantification of escape from X chromosome inactivation with single-cell omics data reveals heterogeneity across cell types and tissues.
Not available
S-EPMC11406184 | biostudies-literature
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