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TranscriptomicsCloning of 50-75 nt small RNAs associated with Armitage in OSCs
Armitage (Armi) is a component of Yb bodies and functions in the primary piRNA processing pathway. Armi interaction with Piwi does not require Yb expression; however, without Yb, the Armi-Piwi complex does not localize at Yb bodies and contains few piR-ILs (small RNAs associated with Armitage compl...
ORGANISM(S): Drosophila melanogaster 
2010-10-24 | E-GEOD-23931 | biostudies-arrayexpress
TranscriptomicsHITS-CLIP analysis of Yb binding sites in Drosophila ovary cell line
piRNAs direct Piwi to repress transposons to maintain genome integrity in Drosophila ovarian somatic cells. piRNA maturation and association with Piwi occur at perinuclear Yb bodies, the centers of piRNA biogenesis. Here, we show that piRNA intermediates arising from the piRNA cluster flamenco (flam...
ORGANISM(S): Drosophila melanogaster 
2014-06-24 | E-GEOD-54875 | biostudies-arrayexpress
TranscriptomicsSomatic Primary piRNA Biogenesis Driven by Cis-Acting RNA Elements and Trans- Acting Yb
Primary piRNAs in Drosophila ovarian somatic cells arise from piRNA cluster transcripts and the 3′ UTRs of a subset of mRNAs, including Traffic jam (Tj) mRNA. However, it is unclear how these RNAs are determined as primary piRNA sources. Here, we identify a cis-acting 100-nt fragment in the Tj 3′ UT...
ORGANISM(S): Drosophila melanogaster 
2015-06-05 | E-GEOD-69625 | biostudies-arrayexpress
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