Isocitrate - OmicsDI

Show results for

Unknown (2154)
Transcriptomics (842)
Genomics (354)
Metabolomics (302)
Proteomics (78)
Methylation profiling (36)
Other (7)
Models (6)

Organisms

Homo sapiens (565)
Mus musculus (232)
Arabidopsis thaliana (19)
Saccharomyces cerevisiae (17)
Streptococcus pneumoniae D39 (16)
Rattus norvegicus (14)
Drosophila melanogaster (11)
Escherichia coli (7)
Danio rerio (6)
Bos taurus (5)
Corynebacterium glutamicum (4)
Solanum lycopersicum (4)
Gallus gallus (4)
Macaca mulatta (3)
Zea mays (3)
Schizosaccharomyces pombe (3)
Oryza sativa (3)
Sus scrofa (3)
Escherichia coli str. K-12 substr. MG1655 (3)
Mycobacterium tuberculosis (2)
Anopheles gambiae (2)
Glycine max (2)
Ovis aries (2)
Plasmodium falciparum (2)
Canis lupus familiaris (2)
Agrobacterium tumefaciens (1)
activated sludge metagenome (1)
Streptococcus dysgalactiae subsp. equisimilis (1)
Saccharum sp. (1)
Amycolatopsis mediterranei S699 (1)

Organisms

Homo sapiens (129)
Mus musculus (62)
Rattus norvegicus (3)
Chlorobium limicola (1)
Burkholderia glumae BGR1 (1)
Burkholderia cenocepacia H111 (1)
Bradyrhizobium diazoefficiens USDA 110 (1)
Trichophyton rubrum (1)
Cytospora mali (1)
Rhodotorula toruloides (1)
Penaeus japonicus (1)
unidentified (1)
Saccharomyces cerevisiae S288C (1)
Escherichia coli K-12 (1)
Chlamydomonas reinhardtii (1)
Escherichia coli str. K-12 substr. MG1655 (1)
Saccharomyces cerevisiae (1)
Drosophila melanogaster (1)
Solanum lycopersicum (1)
Caenorhabditis elegans (1)
Mus (1)
Plasmodium falciparum (1)

Repository

biostudies-arrayexpress (729)
ENA (237)
geo (204)
MetabolomicsWorkbench (171)
MetaboLights (130)
EGA (64)
pride (45)
MassIVE (20)
iProX (11)
BioModels (6)
EVA (3)
jPOST (2)
PeptideAtlas (2)
GNPS (1)

Tissue

Cultured cells (30)
Blood (24)
Liver (12)
Muscle (9)
T-cells (9)
Feces (9)
Bacterial cells (7)
Cecum (6)
Fibroblast cells (5)
Urine (5)
Cells (4)
Glioma cells (4)
Unspecified (4)
Heart (4)
Macrophages (4)
Parasite (3)
Brain (3)
Lung (3)
Plasmodium cells (2)
Bone marrow (2)
Stem cells (2)
Epithelial cells (2)
Plant (2)
Kidney (2)
Spleen (2)
Culture media (1)
Sarcoma (1)
Smooth muscle (1)
Ovarian cancer cells (1)
Multiple tissues (1)

Disease

Cancer (24)
Malaria (15)
Inflammation (6)
Diabetes (6)
Graft versus host disease (5)
Heart disease (5)
Ulcerative colitis (3)
Obesity (3)
COVID-19 (3)
Muscular dystrophy (2)
Metabolic syndrome (2)
Influenza (2)
Cachexia (2)
Bacterial infection (2)
HPV positive (1)
High grade glioblastoma (1)
Primary effusion lymphoma (PEL) (1)
MPN (1)
Oligodendroglioma (1)
Schizophrenia (1)
Leukemia (1)
Breast cancer (1)
Mitochondrial disease (1)
Adrenoleukodystrophy (1)
Scrapie (1)
Genetic disease (1)
Cardiomyopathy (1)
Arthralgia (1)
Mosaic virus infection (1)
Asthma (1)

Technology Type

Mass Spectrometry (209)
ESI (131)
Mass spectrometry (91)
EI (45)
Mass spectrometry assay (35)
Shotgun proteomics (25)
Gel-based experiment (8)
NMR (7)
Bottom-up proteomics (7)
NMR spectroscopy (4)
Data-dependent acquisition (3)
Affinity purification coupled with mass spectrometry proteomics (2)
Illumina HiSeq 2000, HiSeq X Ten, Illumina HiSeq 2500, ILLUMINA (1)
OXFORD_NANOPORE, MinION (1)
Illumina 450K (1)
Illumina_Infinium_HumanMethylation450, Illumina_HumanHT-12v4 (1)
Illumina HumanExome-12v1_A (1)
Illumina HiSeq 1000 (1)
ILLUMINA, Illumina HiSeq 2000 (1)
Illumina HiSeq 2500, Illumina HiSeq 2000 (1)
Illumina HiSeq 2000 (1)
API (1)
All-ion fragmentation (1)
HDMSE (1)
Immunopeptidomics (1)
SRM/MRM (1)
SWATH MS (1)
Top-down proteomics (1)

Instrument Platform

NextSeq 500 (9)
Illumina NovaSeq 6000 (5)
Illumina HiSeq 2000 (4)
Orbitrap Fusion Lumos (4)
Illumina iScan (2)
Illumina MiSeq (2)
Q Exactive HF (2)
Orbitrap Fusion (2)
Synapt G2 HDMS (2)
LTQ (2)
FACSAria III (BD Sciences) (1)
BD FACSAria™ III (1)
Illumina Hybridisation Oven (1)
Illumina Hybridization Oven (1)
Thermal cycler, Eppendorf ThermoMixer C (1)
Promega Maxwell RSC instrument (1)
Leica microtome, 1 mm biopsy punch (1)
HPC (1)
Illumins Hybridisation Oven (1)
10x Genomics Chromium (1)
GeneChip® Scanner 3000 7G (Affymetrix) (1)
Illumina iScan System (1)
GenePix 4000B (1)
Illumina HiSeq 2500 (1)
Illumina HiSeq 4000 (1)
- (1)
6560 Q-TOF LC/MS (1)
AmaZon ETD (1)
LTQ Orbitrap (1)
LTQ Orbitrap Elite (1)

Publication Date

2015 (131)
2013 (116)
2014 (108)
2010 (96)
2012 (93)
2011 (71)
2026 (69)
2024 (64)
2022 (59)
2016 (52)
2025 (48)
2021 (45)
2008 (33)
2023 (30)
2020 (27)
2017 (25)
2019 (22)
2009 (22)
2018 (20)
2007 (13)
2005 (6)
2006 (2)
2004 (1)

CHEBI ID

CHEBI:30769 (72)
CHEBI:18012 (70)
CHEBI:30887 (69)
CHEBI:30915 (61)
CHEBI:6650 (59)
CHEBI:16704 (58)
CHEBI:15428 (58)
CHEBI:32816 (55)
CHEBI:15891 (54)
CHEBI:16335 (54)
CHEBI:16708 (53)
CHEBI:17596 (53)
CHEBI:15741 (52)
CHEBI:17750 (52)
CHEBI:16750 (52)
CHEBI:17822 (51)
CHEBI:17368 (51)
CHEBI:22660 (50)
CHEBI:28044 (50)
CHEBI:29016 (50)
CHEBI:18237 (50)
CHEBI:15354 (50)
CHEBI:27570 (49)
CHEBI:16811 (49)
CHEBI:15351 (32)
CHEBI:16891 (4)
CHEBI:30744 (4)
CHEBI:15380 (4)
CHEBI:15346 (4)
CHEBI:16265 (2)

Metabolite Name

Isocitrate (73)
Citrate (41)
Isocitrate (40)
Taurine (40)
Serine (39)
Proline (39)
Lysine (39)
Cytidine (39)
Aspartate (39)
Arginine (39)
Histidine (39)
Phenylalanine (39)
Tyrosine (39)
Threonine (39)
Glutamine (39)
Alanine (39)
Valine (39)
Fumarate (39)
Succinate (39)
AMP (39)
Glycine (39)
ADP (39)
Alpha-ketoglutarate (39)
Tryptophan (38)
Malate (38)
Inosine (38)
Glutamate (38)
Citrulline (38)
Asparagine (38)
Allantoin (38)

First Public Date

2025 (33)
2024 (29)
2026 (28)
2014 (24)
2021 (23)
2022 (21)
2023 (19)
2017 (17)
2018 (14)
2020 (11)
2013 (6)
2019 (5)
2016 (5)
2015 (2)

Modelling Approach

Ordinary differential equation model (4)
Constraint-based model (2)

Lab affiliation

Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States (2)
Instituto de Ciencia y Tecnología Animal, Universidad Politècnica de València, Valencia, Spain (2)
State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University, Nanjing, China. (2)
Assistant Professor, Faculty of Dentistry, National University of Singapore (1)
Biochemistry and molecular biology department, Universidade Federal de Goias, Brazil (1)
DZNE Munich Neuroproteomics Feodor-Lynen Str. 17 81377 Munich Germany (1)
Departamento de Bioquímica y Biología Molecular B e Inmunología. Facultad de Química. Universidad de Murcia. Campus de Excelencia Mare Nostrum (1)
Department of Biochemistry and Molecular Biology, Rutgers University, Robert Wood Johnson Medical School, USA (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA (1)
Department of Biomedical Science and Environmental Biology, College of Life Science, Kaohsiung Medical University (1)
Department of Chemistry, Boston College (1)
Department of Clinical and Experimental Medicine, Cell Biology, Faculty of Medicine, Linköping University, Linköping, Sweden. Department of Physiology, Ikerbasque, Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU, Spain (1)
Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel (1)
Department of Laboratory Medicine, Lund University, Sweden (1)
Department of Medical Sciences iBiMED University of Aveiro (1)
Department of Neurology, Erasmus University Medical Center Rotterdam (1)
Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany NNF Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark (1)
Director, Advanced Clinical Biosystems Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048 (1)
Département de Neurochirurgie, CHU Angers, Angers, France Inserm UMR 1307, CNRS UMR 6075, Université de Nantes, CRCI2NA, Université d'Angers, Angers, France (1)
ECOBIO (1)
Erasmus MC Department of Neurology Laboratory of Neuro-oncolgy (1)
Faculty of Chemistry and Pharmacy, Ludwig-Maximilians-Universität München, Germany (1)
Federal University of Goias (1)
Head Proteomics Group , Leiden University Medical Center, Center for Proteomics and Metabolomics, PO Box 9600, Postal zone P1-Q, 2300 RC Leiden, The Netherlands (1)
Hebei normal university,China (1)
HuaZhong Agricultural University (1)
Institut Jacques Monod (1)
Institut fuer Mikrobiologie EMAU Greifswald (1)
Institute for Molecular Medicine I Medical Faculty Heinrich-Heine-University Duesseldorf Universitaetsstrasse 1 40225 Duesseldorf Germany (1)

IsPrivate

False (6)

Model Flag

Non Kinetic (1)

Submitter Keywords

Not Peer Reviewed (1)

Classification

bacteria (4)
fungi (1)
protozoa (1)

Study type

Transcription profiling by array (514)
RNA-seq of coding RNA (61)
Methylation profiling by array (37)
Unknown experiment type (23)
Comparative genomic hybridization by array (16)
Genotyping by array (12)
ChIP-seq (11)
RNA-seq of non coding RNA (9)
Other (8)
Methylation profiling by high throughput sequencing (8)
ChIP-chip by tiling array (6)
Transcription profiling by tiling array (3)
Transcription profiling by RT-PCR (3)
Transcription profiling by SAGE (2)
Translation profiling (2)
Human - One-color microarray (2)
DNA-seq (2)
RNA-seq of total RNA (2)
Transcription profiling by MPSS (1)
Differential (1)
MicroRNA profiling by high-throughput sequencing (1)
Human - High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
ChIP-chip by array (1)
MicroRNA profiling by high throughput sequencing (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2022 (272)
2021 (267)
2023 (227)
2020 (214)
2015 (189)
2025 (181)
2024 (174)
2014 (166)
2019 (165)
2013 (157)
2018 (140)
2016 (128)
2010 (119)
2012 (117)
2017 (108)
2011 (90)
2008 (46)
2009 (35)
2026 (26)
2007 (20)
2005 (13)
2006 (7)
2002 (6)
2004 (3)
1999 (3)
2003 (2)
2001 (2)
2000 (2)
1998 (1)
1997 (1)

Previous page
1 / 378
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 378
Next page

Sort by:

Relevance

Page size

Isocitrate dehydrogenase-1/Glioma Fluxomics Study

Not available

ORGANISM(S): Homo sapiens

ST000302 | MetabolomicsWorkbench

Patient glioma microarray for Impaired histone demethylation contributes to the cell differentiation arrest induced by cancer-associated isocitrate dehydrogenase mutation

To study the effects of IDH mutations, we collected and performed gene expression microarray analysis with tumor specimens from patients with grade II-III oligodendroglioma. Sequencing for mutations of IDH1 and IDH2 was done. Gene expression was compared between IDH wildtype vs. mutant samples

ORGANISM(S): Homo sapiens

2012-02-01 | E-MEXP-3239 | biostudies-arrayexpress

Induction of sarcomas by mutant IDH2

More than 50% of patients with chondrosarcomas exhibit gain-of-function mutations in either isocitrate dehydrogenase 1 (IDH1) or IDH2. In this study, we performed genome-wide CpG methylation sequencing of chondrosarcoma biopsies and found that IDH mutations were associated with DNA hypermethylation ...

ORGANISM(S): Homo sapiens

2013-10-21 | E-GEOD-50539 | biostudies-arrayexpress

Whole exome sequencing analyses of human, IDH2-mutated, acute myeloid leukemia samples from patients before or during treatment with Enasidenib.

Mutations in isocitrate dehydrogenase 2 (IDH2) occur in many cancers including Acute Myeloid Leukemia (AML). In preclinical models mutant IDH2 causes partial hemopoietic differentiation arrest. Recently, we showed that single agent Enasidenib, a first-in-class, selective mutant IDH2 inhibitor, produ...

ORGANISM(S): Homo sapiens

2018-08-13 | E-MTAB-6299 | biostudies-arrayexpress

Isocitrate Dehydrogenase 1 Primes Group-3 Medulloblastomas For Cuproptosis

PRJNA1169346 | ENA

Targeting chordoma via an Isocitrate Dehydrogenase-1 dependent susceptibility to redox metabolism

PRJNA1476189 | ENA

Isoform switching as a mechanism of acquired resistance to isocitrate dehydrogenase inhibition

PRJEB29267 | ENA

Decifiency of NADP isocitrate dehydrogenase

PRJNA872936 | ENA

IDH1 mutation defines methylation class and survival in human glioma

Astrocytoma, oligodendroglioma, oligoastrocytoma, and ependymoma are the main histologic subtypes of glioma. The molecular character of these subtypes has profound implications for understanding their causes and treatment. We describe the epigenetic landscape of these tumor types using novel DNA met...

ORGANISM(S): Homo sapiens

2010-12-20 | E-GEOD-20395 | biostudies-arrayexpress

Immune landscape of Isocitrate Dehydrogenase (IDH) stratified human gliomas [RNA-Seq]

PRJNA922462 | ENA

Previous page
1 / 378
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 378
Next page

Sort by:

Relevance

Page size

3779 Results

Show results for

Organisms

Organisms

Repository

Tissue

Disease

Technology Type

Instrument Platform

Publication Date

CHEBI ID

Metabolite Name

First Public Date

Modelling Approach

Lab affiliation

Tags

IsPrivate

Model Flag

Submitter Keywords

Classification

Study type

Release Date

OmicsDI is part of the ELIXIR infrastructure

Tweets