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ModelsBoehm2014 - isoform-specific dimerization of pSTAT5A and pSTAT5B
Boehm2014 - isoform-specific dimerization of pSTAT5A and pSTAT5B To study STAT5 activation, the authors build a dynamic model of pSTAT5 isoform dimerization. Combinatorial binding of pSTAT5A and pSTAT5B is analysed using model hypotheses and concurrent experiments. Model parameters are derived from ...
2024-09-02 | BIOMD0000000591 | BioModels
TranscriptomicsIsoform-specific transcriptional activity of overlapping targets that respond to thyroid hormone receptors a1 and b1
Thyroid hormone receptors (TRs) are hormone-regulated transcription factors that control multiple aspects of physiology and development. TRs are expressed in vertebrates as a series of distinct isoforms that exert distinct biological roles. We wished to determine if the two most widely expressed i...
ORGANISM(S): Homo sapiens 
2009-08-08 | E-GEOD-17561 | biostudies-arrayexpress
ProteomicsProteomic profiling of the oncogenic septin 9 reveals isoform-specific interactions in breast cancer cells
Septins are a family of multimeric GTP-binding proteins, which are abnormally expressed in cancer. Septin 9 (SEPT9) is an essential and ubiquitously expressed septin with multiple isoforms, which have differential expression patterns and effects in breast cancer cells. It is unknown, however, if SEP...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD012977 | Pride
Breast cancer Septin interactome Septins Sept9 
Transcriptomicsdaf-16/FoxO isoform-specific deletion mutants
FoxO transcription factors promote longevity across taxa. How they do so is poorly understood. In the nematode Caenorhabditis elegans, the A- and F-isoforms of the FoxO transcription factor DAF-16 extend life span in the context of reduced DAF-2 insulin-like growth factor receptor (IGFR) signaling. ...
ORGANISM(S): Caenorhabditis elegans 
2015-08-27 | E-GEOD-72426 | biostudies-arrayexpress
GenomicsIsoform-specific depletion of U2AF1
Isoform-specific depletion of U2AF1
PRJEB6651 | ENA
GenomicsIsoform-specific functions of PPARg in gene regulation and adipose metabolism
Isoform-specific functions of PPARg in gene regulation and adipose metabolism
PRJNA773105 | ENA
GenomicsIsoform-specific translational control is evolutionarily conserved in primates
Isoform-specific translational control is evolutionarily conserved in primates
PRJNA961136 | ENA
TranscriptomicsProcessing of Drosophila endo-siRNAs depends on a specific Loquacious isoform
Drosophila melanogaster expresses three classes of small RNAs, which are classified according to their mechanisms of biogenesis. MicroRNAs are ~22-23-nt, ubiquitously expressed small RNAs that are sequentially processed from hairpin-like precursors by Drosha/Pasha and Dcr-1/Loquacious complexes. Mic...
ORGANISM(S): Drosophila melanogaster 
2009-07-30 | E-GEOD-17171 | biostudies-arrayexpress
GenomicsIsoform-specific localization of DNMT3A regulates DNA methylation fidelity at bivalent CpG islands
Isoform-specific localization of DNMT3A regulates DNA methylation fidelity at bivalent CpG islands
PRJNA378927 | ENA
GenomicsCondition-specific 3’ mRNA isoform half-lives and stability elements in yeast
Condition-specific 3’ mRNA isoform half-lives and stability elements in yeast
PRJNA948348 | ENA
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