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TranscriptomicsmiRNA profiling in the plasma of patients with in-stent restenosis (ISR)
Studies of miRNA profiling in the plasma of patients between ISR and non-ISR Venous blood was collected in EDTA in the ward or the cardiac catheterization laboratory before the angiography procedure and heparin administration. Plasma was harvested by centrifugation and stored at -80°C until assayed....
ORGANISM(S): Homo sapiens 
2014-09-02 | E-GEOD-60959 | biostudies-arrayexpress
GenomicsISR pathway activation signatures in MEFs: GCN2 and PERK
ISR pathway activation signatures in MEFs: GCN2 and PERK
PRJNA744201 | ENA
ProteomicsThe integrated stress response regulates 18S nonfunctional rRNA decay in mammals
Abstract - 18S nonfunctional rRNA decay (NRD) detects and eliminates translationally nonfunctional 18S rRNA. While this process is critical for ribosome quality control, the mechanisms underlying nonfunctional 18S rRNA turnover remain elusive, particularly in mammals. Here, we show that mammalian 18...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-12-09 | MSV000096620 | MassIVE
GenomicsHarnessing Viral Strategies to modulate the ISR and Reverse Cognitive Dysfunction
Harnessing Viral Strategies to modulate the ISR and Reverse Cognitive Dysfunction
PRJNA1365879 | ENA
GenomicsISR activation mediates the behavioral and neurophysiological abnormalities in Down syndrome
ISR activation mediates the behavioral and neurophysiological abnormalities in Down syndrome
PRJNA575651 | ENA
GenomicsMapping the ISR Landscape in Cognitive Disorders via single-cell multi-omics
Mapping the ISR Landscape in Cognitive Disorders via single-cell multi-omics
PRJNA1389920 | ENA
GenomicsISR target genes in adipose of maP2-Fv2E-PERK
ISR target genes in adipose of maP2-Fv2E-PERK
PRJNA628653 | ENA
TranscriptomicsThe Small Molecule ISRIB Reverses the Effects of eIF2α Phosphorylation on Translation and Stress Granule Assembly
We recently identified ISRIB as a potent inhibitor of the integrated stress response (ISR). ISRIB renders cells resistant to the effects of eIF2α phosphorylation and enhances long-term memory in rodents (10.7554/eLife.00498). Here we show by genome-wide in vivo ribosome profiling that translation o...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-65778 | biostudies-arrayexpress
GenomicsActivation of ISR/ATF4 signaling depletes HIV reservoir in CD4+ T cells
Activation of ISR/ATF4 signaling depletes HIV reservoir in CD4+ T cells
PRJNA867681 | ENA
GenomicsThe ISR activation confers vulnerability to mitoribosome-targeting antibiotics in melanoma
The ISR activation confers vulnerability to mitoribosome-targeting antibiotics in melanoma
PRJNA737120 | ENA
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