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TranscriptomicsTranscription profiling of human and mouse hematopoietic stem cells and other stages of the hematopoietic hierarchy, and to identify the shared expressed genes among the hematopoietic cells and neural and embryonic stem cells in mouse
Study to determine global gene expression profiles for mouse and human hematopoietic stem cells and other stages of the hematopoietic hierarchy, and to identify the shared expressed genes among the hematopoietic cells and neural and embryonic stem cells in mouse.
ORGANISM(S): Mus musculus 
2007-07-19 | E-CBIL-33 | biostudies-arrayexpress
TranscriptomicsNANOG-OCT4-SOX2 Regulatory Module in Human Embryonic Stem Cells (dataset 2)
The transcription factors Nanog, Oct4 and Sox2 are the master regulators of pluripotency in mouse embryonic stem cells (mESCs), however, their functions in human ESCs (hESCs) have not been rigorously defined. Here we show that the requirements for NANOG, OCT4 and SOX2 in hESCs differ from those in ...
ORGANISM(S): Homo sapiens 
2012-04-05 | E-GEOD-34912 | biostudies-arrayexpress
TranscriptomicsNANOG-OCT4-SOX2 Regulatory Module in Human Embryonic Stem Cells (dataset 3)
The transcription factors Nanog, Oct4 and Sox2 are the master regulators of pluripotency in mouse embryonic stem cells (mESCs), however, their functions in human ESCs (hESCs) have not been rigorously defined. Here we show that the requirements for NANOG, OCT4 and SOX2 in hESCs differ from those in ...
ORGANISM(S): Homo sapiens 
2012-04-05 | E-GEOD-34918 | biostudies-arrayexpress
TranscriptomicsNANOG-OCT4-SOX2 Regulatory Module in Human Embryonic Stem Cells (dataset 4)
The transcription factors Nanog, Oct4 and Sox2 are the master regulators of pluripotency in mouse embryonic stem cells (mESCs), however, their functions in human ESCs (hESCs) have not been rigorously defined. Here we show that the requirements for NANOG, OCT4 and SOX2 in hESCs differ from those in ...
ORGANISM(S): Homo sapiens 
2012-04-05 | E-GEOD-34920 | biostudies-arrayexpress
TranscriptomicsNANOG-OCT4-SOX2 Regulatory Module in Human Embryonic Stem Cells
This SuperSeries is composed of the following subset Series: GSE34904: NANOG-OCT4-SOX2 Regulatory Module in Human Embryonic Stem Cells (dataset 1) GSE34912: NANOG-OCT4-SOX2 Regulatory Module in Human Embryonic Stem Cells (dataset 2) GSE34918: NANOG-OCT4-SOX2 Regulatory Module in Human Embryonic Stem...
ORGANISM(S): Homo sapiens 
2012-04-05 | E-GEOD-34921 | biostudies-arrayexpress
TranscriptomicsNANOG-OCT4-SOX2 Regulatory Module in Human Embryonic Stem Cells (dataset 1)
The transcription factors Nanog, Oct4 and Sox2 are the master regulators of pluripotency in mouse embryonic stem cells (mESCs), however, their functions in human ESCs (hESCs) have not been rigorously defined. Here we show that the requirements for NANOG, OCT4 and SOX2 in hESCs differ from those in ...
ORGANISM(S): Homo sapiens 
2012-04-05 | E-GEOD-34904 | biostudies-arrayexpress
TranscriptomicsArchitecture of thermal adaptation in Exiguobacterium sibiricum strain 255-15: A genome and transcriptome approach
Several microorganisms have wide temperature growth range and versatility to tolerate large thermal fluctuations in diverse environments. To better understand thermal adaptation of psychrotrophs, Exiguobacterium sibiricum strain 255-15 was used, a psychrotrophic bacterium that grows from -5°C to 39...
ORGANISM(S): Exiguobacterium sibiricum 255-15 
2010-05-26 | E-GEOD-10133 | biostudies-arrayexpress
MetabolomicsDeficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease
Non-alcoholic fatty liver is the most common liver disease worldwide. Here, we show that the mitochondrial protein mitofusin 2 (Mfn2) protects against liver disease. Reduced Mfn2 expression was detected in liver biopsies from patients with non-alcoholic steatohepatitis (NASH). Moreover, reduced Mfn2...
2018-01-25 | MTBLS600 | MetaboLights
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